18 Results for "

tachyarrhythmia

" in MedChemExpress (MCE) Product Catalog:
Products (18)

18 Results for "tachyarrhythmia" in MCE Product Catalog:

27
27 Publications Verification
Cat. No.: HY-B1205
CAS No.: 51-55-8
Synonyms: Tropine tropate; DL-Hyoscyamine
Atropine (Tropine tropate) is a competitive muscarinic acetylcholine receptor (mAChR) antagonist with IC50 values of 0.39 and 0.71 nM for Human mAChR M4 and Chicken mAChR M4, respectively. Atropine inhibits ACh-induced relaxations in human pulmonary veins. Atropine can be used for research of anti-myopia and bradycardia .
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27
27 Publications Verification
Cat. No.: HY-B0394
CAS No.: 5908-99-6
Synonyms: Tropine tropate sulfate monohydrate; DL-Hyoscyamine sulfate monohydrate
Target:  

mAChR

Atropine (Tropine tropate) sulfate monohydrate is a competitive muscarinic acetylcholine receptor (mAChR) antagonist with IC50 values of 0.39 and 0.71 nM for Human mAChR M4 and Chicken mAChR M4, respectively. Atropine sulfate monohydrate inhibits ACh-induced relaxations in human pulmonary veins. Atropine sulfate monohydrate can be used for research of anti-myopia and bradycardia .
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27
27 Publications Verification
Cat. No.: HY-B1205A
CAS No.: 55-48-1
Synonyms: Tropine tropate sulfate; DL-Hyoscyamine sulfate; Sulfatropinol
Target:  

mAChR

Atropine (Tropine tropate) sulfate is a competitive muscarinic acetylcholine receptor (mAChR) antagonist with IC50 values of 0.39 and 0.71 nM for Human mAChR M4 and Chicken mAChR M4, respectively. Atropine sulfate inhibits ACh-induced relaxations in human pulmonary veins. Atropine sulfate can be used for research of anti-myopia and bradycardia .
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Cat. No.: HY-B1167
CAS No.: 4360-12-7
Synonyms: Cardiorythmine; (+)-Ajmaline
Ajmaline (Cardiorythmine) is a sodium channel blocking, class 1A anti-arrhythmic agent. Ajmaline blocks HERG currents with an IC50 of 1 μM in HEK cells and 42.3 μM in Xenopus oocytes. Ajmaline can be used for the research of the ventricular tachyarrhythmia .
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Cat. No.: HY-B0772A
CAS No.: 130656-51-8
Synonyms: MS-551
Target:  

Potassium Channel

Research Areas:  

Cardiovascular Disease

Nifekalant hydrochloride (MS-551), a class III antiarrhythmic agent, is a IKr potassium channel blocker with an IC50 of 10 µM. Nifekalant hydrochloride can be used for refractory ventricular tachyarrhythmias research .
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Cat. No.: HY-111013
CAS No.: 955371-84-3
Purity:  93.3%
VK-II-86 is a Carvedilol (HY-B0006) analogue lacking antagonist activity at β-adrenoceptors, in hypokalaemia. VK-II-86 prevents hypokalaemia-induced ventricular arrhythmia through multi-channel effects. VK-II-86 prevents all hypokalaemia-induced changes in ion channel activity and oxidative stress .
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Cat. No.: HY-126028A
CAS No.: 30236-32-9
Purity:  98.82%
Synonyms: (S)-Sotalol
(+)-Sotalol ((S)-Sotalol) is the S-isomer of Sotalol (HY-103196). Sotalol is an orally active, non-selective β-adrenergic receptor blocker. (+)-Sotalol is an antiarrhythmic agent. (+)-Sotalol can prolong action potential duration in isolated cardiac muscle .
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Cat. No.: HY-101245
CAS No.: 88069-49-2
Purity:  99.94%
Synonyms: SUN-1165; Pilzicainidehydrochloride
Pilsicainide hydrochloride (SUN-1165) is an orally active sodium channel blocker and potent class Ic antiarrhythmic agent .
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Cat. No.: HY-106912A
CAS No.: 161799-18-4
Synonyms: MK 499 free base
Target:  

Potassium Channel

Research Areas:  

Cardiovascular Disease

L-706000 (MK 499) free base is a potent hERG channel blocker with an IC50 of 32 nM. L-706000 free base is a class III antiarrhythmic agent that can be used for the study of malignant ventricular tachyarrhythmias .
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Cat. No.: HY-133715
CAS No.: 88069-67-4
Synonyms: SUN 1165 free base; Pilzicainide
Target:  

Sodium Channel

Research Areas:  

Cardiovascular Disease

Pilsicainide (SUN 1165 free acid) is a potent sodium channel blocker and potent class Ic antiarrhythmic agent .
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Cat. No.: HY-B1205AR
CAS No.: 55-48-1
Synonyms: Tropine tropate sulfate (Standard); DL-Hyoscyamine sulfate (Standard); Sulfatropinol (Standard)
Atropine (sulfate) (Standard) is the analytical standard of Atropine (sulfate). This product is intended for research and analytical applications. Atropine (Tropine tropate) sulfate is a competitive muscarinic acetylcholine receptor (mAChR) antagonist with IC50 values of 0.39 and 0.71 nM for Human mAChR M4 and Chicken mAChR M4, respectively. Atropine sulfate inhibits ACh-induced relaxations in human pulmonary veins. Atropine sulfate can be used for research of anti-myopia and bradycardia .
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Cat. No.: HY-B0772
CAS No.: 130636-43-0
Synonyms: MS-551 free base
Target:  

Potassium Channel

Research Areas:  

Cardiovascular Disease

Nifekalant (MS-551), a class III antiarrhythmic agent, is a IKr potassium channel blocker with an IC50 of 10 μM. Nifekalant can be used for refractory ventricular tachyarrhythmias research .
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Cat. No.: HY-B0772AR
CAS No.: 130656-51-8
Synonyms: MS-551 (Standard)
Nifekalant (hydrochloride) (Standard) is the analytical standard of Nifekalant (hydrochloride). This product is intended for research and analytical applications. Nifekalant hydrochloride (MS-551), a class III antiarrhythmic agent, is a IKr potassium channel blocker with an IC50 of 10 µM. Nifekalant hydrochloride can be used for refractory ventricular tachyarrhythmias research .
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Cat. No.: HY-B1167R
CAS No.: 4360-12-7
Synonyms: Cardiorythmine (Standard); (+)-Ajmaline (Standard)
Ajmaline (Standard) is the analytical standard of Ajmaline. This product is intended for research and analytical applications. Ajmaline (Cardiorythmine) is a sodium channel blocking, class 1A anti-arrhythmic agent. Ajmaline blocks HERG currents with an IC50 of 1 μM in HEK cells and 42.3 μM in Xenopus oocytes. Ajmaline can be used for the research of the ventricular tachyarrhythmia .
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Cat. No.: HY-B1205B
CAS No.: 6415-90-3
Synonyms: Tropine tropate hydrobromide; DL-Hyoscyamine hydrobromide
Target:  

mAChR

Atropine (Tropine tropate) hydrobromide is a competitive muscarinic acetylcholine receptor (mAChR) antagonist with IC50 values of 0.39 and 0.71 nM for Human mAChR M4 and Chicken mAChR M4, respectively. Atropine hydrobromide inhibits ACh-induced relaxations in human pulmonary veins. Atropine hydrobromide can be used for research of anti-myopia and bradycardia .
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Cat. No.: HY-B0394R
CAS No.: 5908-99-6
Synonyms: Tropine tropate sulfate monohydrate (Standard); DL-Hyoscyamine sulfate monohydrate (Standard)
Atropine (sulfate monohydrate) (Standard) is the analytical standard of Atropine (sulfate monohydrate). This product is intended for research and analytical applications. Atropine (Tropine tropate) sulfate monohydrate is a competitive muscarinic acetylcholine receptor (mAChR) antagonist with IC50 values of 0.39 and 0.71 nM for Human mAChR M4 and Chicken mAChR M4, respectively. Atropine sulfate monohydrate inhibits ACh-induced relaxations in human pulmonary veins. Atropine sulfate monohydrate can be used for research of anti-myopia and bradycardia .
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Cat. No.: HY-W710915
Aprindine hydrochloride-d10 is the deuterium labeled Aprindine hydrochloride (HY-A0236A). Aprindine hydrochloride is a class I-b anti-arrhythmic agent and a hERG channel blocker with an IC50 of 0.23 μM. Aprindine hydrochloride has inhibitory effects on Na+/Ca2+ exchanger currents, which is partly responsible for their antiarrhythmic and cardioprotective effects. Aprindine hydrochloride is widely used for trial and ventricular tachyarrhythmias research research.
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Cat. No.: HY-105439A
CAS No.: 68379-03-3
Synonyms: LY 150378
Target:  

Drug Derivative

Research Areas:  

Cardiovascular Disease

Clofilium phosphate (LY 150378) is an antiarrhythmic/antifibrillatory agent. Clofilium phosphate significantly prolongs the action potential duration and effective refractory period of canine cardiac Purkinje fibers, increases the ventricular fibrillation threshold, reduces the risk of reentrant arrhythmias, and enables spontaneous conversion of some ventricular fibrillation episodes to sinus rhythm. Clofilium phosphate is applicable to research related to ventricular fibrillation, arrhythmias, and ventricular tachyarrhythmias .
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