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Cat. No.: HY-W710915

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Aprindine hydrochloride-d₁₀

Aprindine hydrochloride-d₁₀ is the deuterium labeled Aprindine hydrochloride (HY-A0236A). Aprindine hydrochloride is a class I-b anti-arrhythmic agent and a hERG channel blocker with an IC₅₀ of 0.23 μM. Aprindine hydrochloride has inhibitory effects on Na+/Ca2+ exchanger currents, which is partly responsible for their antiarrhythmic and cardioprotective effects. Aprindine hydrochloride is widely used for trial and ventricular tachyarrhythmias research research.

For research use only. We do not sell to patients.

Formula: C₂₂H₂₁D₁₀ClN₂
Molecular Weight:369.01

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (246 KB)

Aprindine hydrochloride-d₁₀ Chemical Structure

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Biological Activity
- Description
- In Vitro
- Application
Chemical Information
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Biological Activity

Description

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Application

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

Unlabeled Cas 33237-74-0
Molecular Weight 369.01
Formula C₂₂H₂₁D₁₀ClN₂
SMILES

[2H]C(C([2H])([2H])[2H])(N(CCCN(C1CC2=CC=CC=C2C1)C3=CC=CC=C3)C([2H])(C([2H])([2H])[2H])[2H])[2H].Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.