2 Results for "

tgfbr1+inhibitor

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "tgfbr1+inhibitor" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-136244
CAS No.: 1801333-55-0
Purity:  99.29%
Target:  

TGF-β Receptor

Research Areas:  

Cancer

PF-06952229 is a potent, selective and orally active TGFbR1 inhibitor. PF-06952229 specifically binds to TGFbR1 and prevents TGFbR1-mediated signal transduction.?PF-06952229 is a promising antineoplastic?agent for the study solid tumors, especifically metastatic breast cancer [1].
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Cat. No.: HY-164793
CAS No.: 733806-89-8
Research Areas:  

Infection

TGFBR1-IN-2 (Compound AQA) is a TGFBR1 inhibitor and an antibacterial agent. TGFBR1-IN-2 is a substrate for cytochrome P450s. TGFBR1-IN-2 contains the pyridyl-6-methyl moiety necessary for Mycobacterium tuberculosis inhibition and has potent inhibitory activity against non-replicating and persistent Mycobacterium tuberculosis [1].
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