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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10 Results for "
transcription factor EB
" in MedChemExpress (MCE) Product Catalog:
Products (10)
10 Results for "transcription factor EB" in MCE Product Catalog:
5
5 Cited Publications
Cat. No.: HY-N0866
CAS No.: 54706-99-9
Category:
Terpenoids Euphorbia kansui T. N. Liou ex S. B. Ho Euphorbiaceae Diterpenoids Plants Disease Research Fields Inflammation/Immunology
Target:
1
1 Cited Publications
NEO214 is an autophagy inhibitor and a covalent conjugate of the PDE4 inhibitor Rolipram (HY-16900) and perillyl alcohol (HY-N7000). It has anti-cancer activity and blood-brain barrier (BBB) permeability. Over sex. NEO214 prevents autophagy-lysosome fusion, thereby blocking autophagic flux and triggering glioma cell death. The process involves mTOR activation, andTFEB(Transcription Factor EB) aggregation. NEO214 inhibitionMacroautophagy/autophagy in glioblastoma cells has the potential to overcome chemotherapy resistance in glioblastoma .
1
1 Cited Publications
Cat. No.: HY-P701228
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TFEB; Class E Basic Helix-Loop-Helix Protein 35; transcription factor EB; T-Cell transcription factor EB; BHLHe35; ALPHATFEB; TCFEB; BHLHE35
Species:
Human
Source:
E. coli
Cat. No.: HY-148230
Purity: 90.24%
Research Areas:
TFEB Decoy ODN sodium is a synthetic oligonucleotide with a hairpin ring structure, which were designed to inhibit Transcription factor EB (TFEB). TFEB decoy ODN inhibited fibrosis and autophagy in a UUO mouse model. The TFEB decoy ODNs also showed anti-inflammatory effects.
Cat. No.: HY-162866
Target:
Research Areas:
CXM102 is an autophagy activator. CXM102 can induce autophagy in aged BMSCs, leading to the rejuvenation of BMSCs and preferential differentiation into osteoblasts. CXM102 promotes the nuclear translocation of transcription factor EB (TFEB) and the formation of osteoblasts. CXM102 can stimulate bone synthesis metabolism in middle-aged male mice, reduce bone marrow adipocytes, delay bone loss, lower serum inflammation levels, decrease organ fibrosis, and extend the lifespan of the mice .
Cat. No.: HY-P706198
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Lytic switch protein BZLF1; EB1; Protein Z; Trans-activator protein BZLF1; Zta 1; bZIP transcription factor ZEBRA; BZLF1
Species:
Virus
Source:
E. coli
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
