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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
viable epidermis
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "viable epidermis" in MCE Product Catalog:
Cat. No.: HY-131577A
CAS No.: 42613-33-2
Synonyms: Dispase I
Neutral protease I (Dispase I) is a rapid, effective, gentle and neutral protease that can separate intact epidermis from the dermis. Neutral protease I can also separate intact epithelial sheets in culture from the substratum. Neutral protease I preserves the viability of the epithelial cells while cleaving the basement membrane zone region. Neutral protease I can also be used to prevent clumping in suspension cultures. Neutral protease I cleaves fibronectin and type IV collagen, but not laminin, type V collagen, serum albumin, or transferrin .
Cat. No.: HY-164381
CAS No.: 74512-12-2
Omoconazole is an imidazole-derived azole antifungal agent. Omoconazole exhibits broad-spectrum in vitro activity against dermatophytes, yeasts, and dimorphic fungi, exerting fungistatic effects at low concentrations and fungicidal effects at high concentrations. Omoconazole accumulates in the skin, binds to keratin, and is slowly transferred from the stratum corneum to the viable epidermis. Omoconazole inhibits the growth of dermatophytes, impairs daughter cell separation in Candida albicans, induces cell wall thickening, disrupts intracellular cytoplasmic organelles, and leads to cell death. Omoconazole is used in studies related to dermatophytosis and superficial fungal infections .
Cat. No.: HY-D3047I
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Rhodamine B-Dextran (chloride) (MW 500000) is a Rhodamine B (HY-Y0016)-labeled dextran with a molecular weight of 500000. Rhodamine B-Dextran (chloride) (MW 500000) is a fluorescent dye used to track the diffusion of macromolecules in ex vivo human skin. Rhodamine B-Dextran (chloride) (MW 500000) is delivered to skin layers via the Nanopatch microneedle array, which physically disrupts the stratum corneum and dermal-epidermal junction barriers to deposit the dye directly into epidermal and dermal regions; fluorescence is detected via multiphoton microscopy, and fluorescence intensity is assumed to be roughly proportional to dye concentration .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
