1. Apoptosis
    Protein Tyrosine Kinase/RTK
    JAK/STAT Signaling
    Stem Cell/Wnt
    MAPK/ERK Pathway
    NF-κB
  2. Apoptosis
    EGFR
    ERK
    NF-κB
  3. Sulforaphene

Sulforaphene 

Cat. No.: HY-N2450 Purity: 98.01%
Handling Instructions

Sulforaphene, isolated from radish seeds, exhibits an ED50 against velvetleaf seedlings approximately 2 x 10-4 M. Sulforaphene promotes cancer cells apoptosis and inhibits migration via inhibiting EGFR, p-ERK1/2, NF‐κB and other signals.

For research use only. We do not sell to patients.

Sulforaphene Chemical Structure

Sulforaphene Chemical Structure

CAS No. : 592-95-0

Size Price Stock Quantity
5 mg USD 119 In-stock
Estimated Time of Arrival: December 31
10 mg USD 202 In-stock
Estimated Time of Arrival: December 31
20 mg USD 343 In-stock
Estimated Time of Arrival: December 31
50 mg   Get quote  
100 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

Sulforaphene, isolated from radish seeds, exhibits an ED50 against velvetleaf seedlings approximately 2 x 10-4 M. Sulforaphene promotes cancer cells apoptosis and inhibits migration via inhibiting EGFR, p-ERK1/2, NF‐κB and other signals[1][2][3][4].

Molecular Weight

175.27

Formula

C₆H₉NOS₂

CAS No.
SMILES

O=S(/C=C/CCN=C=S)C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (570.55 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.7055 mL 28.5274 mL 57.0548 mL
5 mM 1.1411 mL 5.7055 mL 11.4110 mL
10 mM 0.5705 mL 2.8527 mL 5.7055 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (14.26 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (14.26 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (14.26 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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Keywords:

SulforapheneApoptosisEGFRERKNF-κBEpidermal growth factor receptorErbB-1HER1Extracellular signal regulated kinasesNuclear factor-κBNuclear factor-kappaBInhibitorinhibitorinhibit

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Product Name:
Sulforaphene
Cat. No.:
HY-N2450
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