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Cat. No.: HY-156452

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T-1-MCPAB

T-1-MCPAB is a VEGFR-2 inhibitor (IC₅₀=0.135 µM) that effectively inhibits MCF7 migration. T-1-MCPAB can be used in cancer research.

For research use only. We do not sell to patients.

Formula: C₂₂H₁₉ClN₆O₄
Molecular Weight:466.88

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

T-1-MCPAB Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

T-1-MCPAB is a VEGFR-2 inhibitor (IC₅₀=0.135 µM) that effectively inhibits MCF7 migration. T-1-MCPAB can be used in cancer research^[1].

IC₅₀ & Target^[1].

VEGFR-2

0.135 μM (IC₅₀)

All VEGFR Isoforms :

Chemical Information

Molecular Weight 466.88
Formula C₂₂H₁₉ClN₆O₄
SMILES

CN(C(N1CC(NC2=CC=C(C(NC3=CC=CC(Cl)=C3)=O)C=C2)=O)=O)C(N=CN4C)=C4C1=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Eissa IH, et al. Anti-breast cancer potential of a new xanthine derivative: In silico, antiproliferative, selectivity, VEGFR-2 inhibition, apoptosis induction and migration inhibition studies. Pathol Res Pract. 2023 Nov;251:154894. [Content Brief]

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Amount: USD 0.00

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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T-1-MCPAB

All VEGFR Isoforms