α-Eleostearic acid
Based on 1 publication(s) in Google Scholar
α-Eleostearic acid (cis-Eleostearic acid), a conjugated linolenic acid, is an apoptosis inducer. α-Eleostearic acid is also a ferroptosis inducer. α-Eleostearic acid exhibits antioxidant and antitumor activity.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 506-23-0
- 화학식: C18H30O2
- 분자량:278.43
-
보관:Shipping with dry ice
-80°C, protect from light, stored under nitrogen
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Protocol
- 순도&문서
- References
-
Help & FAQs
-
HY-139066
Punicic acidBioactive Compound -
HY-141553
Methyl alpha-eleostearateBiochemical Assay Reagent -
HY-131405
β-Eleostearic acidApoptosis Inducer -
HY-121457
9-NitrooleateNitrated Fatty Acid -
HY-116538
(10E,12Z)-Octadeca-10,12-dienoic acidPPARα Activator -
HY-113162
Bovinic acidAnti-inflammatory Agent -
HY-139114
20-Carboxyarachidonic acidPPARalpha/PPARgamma Activator -
HY-131616
Ethyl α-eleostearateAnti-neuroinflammation -
HY-113102B
9(Z),11(Z)-Octadecadienoic acidLinoleic Acid Isomer -
HY-113162A
Bovinic acid sodiumFatty Acid -
HY-113162R
Bovinic acid (Standard)Standard -
HY-121619
Jacaric acidAnticancer Agent
Publications Citing Use of MedChemExpress (MCE) α-Eleostearic acid
More
Biological Activity
제품 설명
In Vitro
α-Eleostearic acid (0-40 μM; 24 h) inhibits the growth of some cancer and fibroblast cell lines, including those of HL60 leukemia and HT29 colon carcinoma[1].
α-Eleostearic acid (20 μM; 6 h) induced cellular and nuclear fragmentation, and nucleosomal DNA fragmentation typical of apoptosis in HL60 leukemia cells[1].
α-Eleostearic acid (0.01-100 μM; 72 h) triggers death of MDA-MB-231 cells and this death was suppressed by Fer-1, Deferoxamine, and vitamin E[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
Oral administration of tung oil, naturally rich inα-Eleostearic acid, to mice limits tumor growth and metastasis in an aggressive TNBC orthotopic xenograft model[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 506-23-0
-
Appearance Liquid
-
분자량 278.43
-
화학식 C18H30O2
-
Color Colorless to light yellow
-
SMILES
CCCC/C=C/C=C/C=C\CCCCCCCC(O)=O
-
Synonyms
cis-Eleostearic acid
-
선적
Shipping with dry ice.
-
보관
-80°C, protect from light, stored under nitrogen
Publications (1)
-
Journal Impact Factor
-
Most Recent
-
Nat Cell Biol
2026 Jun;28(6):1204-1218. PMID: 42174134
순도&문서
-
Data Sheet (268 KB)
-
SDS (645 KB)
- English - EN (645 KB)
- Français - FR (645 KB)
- Deutsch - DE (645 KB)
- Norwegian - NO (645 KB)
- Español - ES (645 KB)
- Swedish - SV (645 KB)
- Italian - IT (645 KB)
- Korean - KR (645 KB)
- Portuguese - PT (645 KB)
-
Handling Instructions (2659 KB)
References
[1]. Kobori M, et, al. Alpha-eleostearic acid and its dihydroxy derivative are major apoptosis-inducing components of bitter gourd. J Agric Food Chem. 2008 Nov 26;56(22):10515-20. [Content Brief]
[2]. Saha SS, et, al. Comparative study of antioxidant activity of alpha-eleostearic acid and punicic acid against oxidative stress generated by sodium arsenite. Food Chem Toxicol. 2009 Oct;47(10):2551-6. [Content Brief]
[3]. Beatty A, et, al. Ferroptotic cell death triggered by conjugated linolenic acids is mediated by ACSL1. Nat Commun. 2021 Apr 14;12(1):2244. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
α-Eleostearic acid Related Classifications
HY-27787 Related Classifications
Powered by Bioz