1,1,3-Tribromoacetone
Based on 1 publication(s) in Google Scholar
1,1,3-Tribromoacetone is an impurity of Methotrexate (HY-14519). Methotrexate, an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 3475-39-6
- Formula: C3H3Br3O
- Molecular Weight:294.77
-
Storage:Pure form -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
-
Bioactive Compound Library Max
HY-L181
-
Bioactive Compound Library
HY-L001
-
Metabolism/Protease Compound Library
HY-L012
-
Anti-Cancer Compound Library
HY-L025
-
Drug Metabolite Library
HY-L098
-
Cysteine Targeted Covalent Library
HY-L153
-
Cysteine Targeted Covalent Fragment Library
HY-L154
-
MCE Bioactive Compound Library
HY-L001V
-
High-Throughput Bioactive Compound Library
HY-L205
Publications Citing Use of MedChemExpress (MCE) 1,1,3-Tribromoacetone
More
Biological Activity
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 3475-39-6
-
Appearance Oil
-
Molecular Weight 294.77
-
Formula C3H3Br3O
-
Color Colorless to light yellow
-
SMILES
O=C(CBr)C(Br)Br
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
-
Journal Impact Factor
-
Most Recent
-
Anal Chem
Exposome-Scale Investigation of Cl-/Br-Containing Chemicals Using High-Resolution Mass Spectrometry, Multistage Machine Learning, and Cloud Computing. [Abstract]2025 Jun 3;97(21):11099-11109. PMID: 40401576
Solvent & Solubility
DMSO : 100 mg/mL (339.25 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (272 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
References
[2]. [2].Swierkot J, et al. Methotrexate in rheumatoid arthritis. Pharmacol Rep. 2006 Jul-Aug;58(4):473-92 [Content Brief]
[3]. Banji D, et al. Evaluation of the concomitant use of methotrexate and curcumin on Freund's complete adjuvant-induced arthritis and hematological indices in rats. Indian J Pharmacol. 2011;43(5):546-550. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.3925 mL | 16.9624 mL | 33.9248 mL | 84.8119 mL |
| 5 mM | 0.6785 mL | 3.3925 mL | 6.7850 mL | 16.9624 mL | |
| 10 mM | 0.3392 mL | 1.6962 mL | 3.3925 mL | 8.4812 mL | |
| 15 mM | 0.2262 mL | 1.1308 mL | 2.2617 mL | 5.6541 mL | |
| 20 mM | 0.1696 mL | 0.8481 mL | 1.6962 mL | 4.2406 mL | |
| 25 mM | 0.1357 mL | 0.6785 mL | 1.3570 mL | 3.3925 mL | |
| 30 mM | 0.1131 mL | 0.5654 mL | 1.1308 mL | 2.8271 mL | |
| 40 mM | 0.0848 mL | 0.4241 mL | 0.8481 mL | 2.1203 mL | |
| 50 mM | 0.0678 mL | 0.3392 mL | 0.6785 mL | 1.6962 mL | |
| 60 mM | 0.0565 mL | 0.2827 mL | 0.5654 mL | 1.4135 mL | |
| 80 mM | 0.0424 mL | 0.2120 mL | 0.4241 mL | 1.0601 mL | |
| 100 mM | 0.0339 mL | 0.1696 mL | 0.3392 mL | 0.8481 mL |
1,1,3-Tribromoacetone Related Classifications
HY-133624 Related Classifications
Powered by Bioz