1,8-Diamino-4,5-dihydroxyanthraquinone
1,8-Diamino-4,5-dihydroxyanthraquinone is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
For research use only. We do not sell to patients.
- CAS No.: 128-94-9
- Formula: C14H10N2O4
- Molecular Weight:270.24
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HEK-293T | CC50 |
>250 μM
Compound: 2
|
Cytotoxicity against human HEK293T cells assessed as decrease in cell viability by MTT assay
Cytotoxicity against human HEK293T cells assessed as decrease in cell viability by MTT assay
|
[PMID: 25856229] |
| HEK-293T | IC50 |
16 μM
Compound: 24; AL18
|
Inhibition of Influenza A virus A/WSN/1933(H1N1) PA/PB1 interaction transfected in HEK293T cells assessed as inhibition of viral growth measured after 24 hrs by minireplicon assay
Inhibition of Influenza A virus A/WSN/1933(H1N1) PA/PB1 interaction transfected in HEK293T cells assessed as inhibition of viral growth measured after 24 hrs by minireplicon assay
|
[PMID: 27046062] |
| MDCK | CC50 |
>250 μM
Compound: 24; AL18
|
Cytotoxicity against MDCK cells measured after 24 to 120 hrs by MTT assay
Cytotoxicity against MDCK cells measured after 24 to 120 hrs by MTT assay
|
[PMID: 27046062] |
| MDCK | EC50 |
13 μM
Compound: 24; AL18
|
Antiviral activity at Influenza A virus infected in MDCK cells by plaque reduction assay
Antiviral activity at Influenza A virus infected in MDCK cells by plaque reduction assay
|
[PMID: 27046062] |
| MDCK | EC50 |
14 μM
Compound: 24; AL18
|
Inhibition of Influenza A virus A/PR/8/34(H1N1) RNA-dependent-RNA polymerase transfected in MDCK cells assessed as reduction in viral growth after 24 hrs by minireplicon assay
Inhibition of Influenza A virus A/PR/8/34(H1N1) RNA-dependent-RNA polymerase transfected in MDCK cells assessed as reduction in viral growth after 24 hrs by minireplicon assay
|
[PMID: 27046062] |
| MDCK | EC50 |
14.5 μM
Compound: 2
|
Antiviral activity against Influenza A virus (A/PR/8/34) (H1N1) infected in MDCK cells assessed as reduction in plaque formation after 48 hrs by plaque reduction assay
Antiviral activity against Influenza A virus (A/PR/8/34) (H1N1) infected in MDCK cells assessed as reduction in plaque formation after 48 hrs by plaque reduction assay
|
[PMID: 25856229] |
| MDCK | EC50 |
8.3 μM
Compound: 24; AL18
|
Inhibition of Influenza B virus B/Lee/40 RNA-dependent-RNA polymerase transfected in MDCK cells assessed as reduction in viral growth after 24 hrs by minireplicon assay
Inhibition of Influenza B virus B/Lee/40 RNA-dependent-RNA polymerase transfected in MDCK cells assessed as reduction in viral growth after 24 hrs by minireplicon assay
|
[PMID: 27046062] |
Chemical Information
-
CAS No. 128-94-9
-
Molecular Weight 270.24
-
Formula C14H10N2O4
-
SMILES
O=C1C2=C(C(O)=CC=C2N)C(C3=C(O)C=CC(N)=C13)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)