15-Hydroxy-7-oxodehydroabietic acid
15-Hydroxy-7-oxodehydroabietic acid is a Diterpenoids product that can be isolated from the herbs of Pinus massoniana.
For research use only. We do not sell to patients.
- CAS No.: 95416-25-4
- Formula: C20H26O4
- Molecular Weight:330.42
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
>10 μM
Compound: 24
|
Cytotoxicity in human A549 cells by SRB assay
Cytotoxicity in human A549 cells by SRB assay
|
[PMID: 26812172] |
| HCT-116 | IC50 |
>10 μM
Compound: 24
|
Cytotoxicity in human HCT116 cells by SRB assay
Cytotoxicity in human HCT116 cells by SRB assay
|
[PMID: 26812172] |
| HEK293 | IC50 |
>100 μg/mL
Compound: 47
|
Inhibition of TNF-alpha-induced NF-kappaB activity in human pNF-kappaB-luc-293 cells
Inhibition of TNF-alpha-induced NF-kappaB activity in human pNF-kappaB-luc-293 cells
|
[PMID: 20022253] |
| HL-60 | IC50 |
>100 μM
Compound: 19
|
Cytotoxicity against human HL60 cells after 48 hrs by MTT assay
Cytotoxicity against human HL60 cells after 48 hrs by MTT assay
|
[PMID: 19746919] |
| LoVo | IC50 |
>25 μg/mL
Compound: 47
|
Antiproliferative activity against human LoVo cells
Antiproliferative activity against human LoVo cells
|
[PMID: 20022253] |
| QGY-7703 | IC50 |
>25 μg/mL
Compound: 47
|
Antiproliferative activity against human QGY7703 cells
Antiproliferative activity against human QGY7703 cells
|
[PMID: 20022253] |
| Raji | IC50 |
238 molar ratio
Compound: 19
|
Inhibition of TPA-induced EBV early antigen activation in human Raji cells relative to TPA
Inhibition of TPA-induced EBV early antigen activation in human Raji cells relative to TPA
|
[PMID: 19746919] |
| RAW264.7 | IC50 |
44 μg/mL
Compound: 47
|
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO release
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO release
|
[PMID: 20022253] |
| SK-MEL-2 | IC50 |
>10 μM
Compound: 24
|
Cytotoxicity in human SK-MEL-2 cells by SRB assay
Cytotoxicity in human SK-MEL-2 cells by SRB assay
|
[PMID: 26812172] |
| SK-OV-3 | IC50 |
>10 μM
Compound: 24
|
Cytotoxicity in human SKOV3 cells by SRB assay
Cytotoxicity in human SKOV3 cells by SRB assay
|
[PMID: 26812172] |
Chemical Information
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CAS No. 95416-25-4
-
Molecular Weight 330.42
-
Formula C20H26O4
-
SMILES
C[C@@]12[C@](CC(C3=CC(C(C)(O)C)=CC=C32)=O)([H])[C@@](C)(CCC1)C(O)=O
-
Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)