2,6-Dimethylbenzoquinone
Based on 1 Customer Validation
2,6-Dimethylbenzoquinone (2,6-DMBQ) is a benzoquinone derivative. 2,6-Dimethylbenzoquinone promotes Photosystem II-mediated photoelectrochemical water oxidation via electron transfer between spinach chloroplast Photosystem II membranes and carbon paste electrodes, and accepts electrons from Photosystem II during oxygen evolution assays. 2,6-Dimethylbenzoquinone undergoes direct photolysis in aqueous solution under 365 nm conditions, producing 2,6-dimethylhydroquinone and 3-hydroxy-2,6-dimethylbenzoquinone.
For research use only. We do not sell to patients.
- Purity: 99.36%
- CAS No.: 527-61-7
- Formula: C8H8O2
- Molecular Weight:136.15
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A2780 | IC50 |
3.2 μM
Compound: 14
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Growth inhibition of human A2780 cells after 72 hrs by SRB assay
Growth inhibition of human A2780 cells after 72 hrs by SRB assay
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[PMID: 29519737] |
| A2780cis | IC50 |
2.9 μM
Compound: 14
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Growth inhibition of human A2780cis cells after 72 hrs by SRB assay
Growth inhibition of human A2780cis cells after 72 hrs by SRB assay
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[PMID: 29519737] |
| K562 | IC50 |
1.25 μM
Compound: 4
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In vitro cytotoxicity against Human Chronic Leukemia K562 cells
In vitro cytotoxicity against Human Chronic Leukemia K562 cells
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[PMID: 8558523] |
| OVCAR-8 | IC50 |
5.2 μM
Compound: 14
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Growth inhibition of human OVCAR8 cells after 72 hrs by SRB assay
Growth inhibition of human OVCAR8 cells after 72 hrs by SRB assay
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[PMID: 29519737] |
2,6-Dimethylbenzoquinone (0.75-1% (w/w); within 10 h) functions as an electron-transfer mediator between spinach chloroplast PS-II-enriched membranes and a carbon paste electrode, generating an anodic steady-state photocurrent under illumination that follows Michaelis-Menten kinetics with a K'DMQ of 0.97 mM and a maximum limiting current of 13.4 μA[1].
2,6-dimethylbenzoquinone (19 μM; up to 30 min irradiated at 365 nm) undergoes direct photodegradation with a quantum yield of 0.47, producing DMHQ and OHDMBQ, while slow dark reaction yields only trace DMHQ, with no significant pH dependence in the range 2.90-6.00[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 527-61-7
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Appearance Solid
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Molecular Weight 136.15
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Formula C8H8O2
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Color Light yellow to yellow
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SMILES
O=C1C(C)=CC(C=C1C)=O
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Synonyms
2,6-DMBQ
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (734.48 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (275 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 7.3448 mL | 36.7242 mL | 73.4484 mL | 183.6210 mL |
| 5 mM | 1.4690 mL | 7.3448 mL | 14.6897 mL | 36.7242 mL | |
| 10 mM | 0.7345 mL | 3.6724 mL | 7.3448 mL | 18.3621 mL | |
| 15 mM | 0.4897 mL | 2.4483 mL | 4.8966 mL | 12.2414 mL | |
| 20 mM | 0.3672 mL | 1.8362 mL | 3.6724 mL | 9.1811 mL | |
| 25 mM | 0.2938 mL | 1.4690 mL | 2.9379 mL | 7.3448 mL | |
| 30 mM | 0.2448 mL | 1.2241 mL | 2.4483 mL | 6.1207 mL | |
| 40 mM | 0.1836 mL | 0.9181 mL | 1.8362 mL | 4.5905 mL | |
| 50 mM | 0.1469 mL | 0.7345 mL | 1.4690 mL | 3.6724 mL | |
| 60 mM | 0.1224 mL | 0.6121 mL | 1.2241 mL | 3.0604 mL | |
| 80 mM | 0.0918 mL | 0.4591 mL | 0.9181 mL | 2.2953 mL | |
| 100 mM | 0.0734 mL | 0.3672 mL | 0.7345 mL | 1.8362 mL |
2,6-Dimethylbenzoquinone Related Classifications
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