2’-Deoxy-2’-fluoro-β-D-arabino-6-azauridine
Based on 1 Customer Validation
2’-Deoxy-2’-fluoro-β-D-arabino-6-azauridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
For research use only. We do not sell to patients.
- Purity: 96.87%
- CAS No.: 908129-24-8
- Formula: C8H10FN3O5
- Molecular Weight:247.18
-
Storage:
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Biological Activity
Description
Chemical Information
-
CAS No. 908129-24-8
-
Appearance Solid
-
Molecular Weight 247.18
-
Formula C8H10FN3O5
-
Color Off-white to light yellow
-
SMILES
O[C@H]1[C@H](F)[C@H](N2C(NC(C=N2)=O)=O)O[C@@H]1CO
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Solvent & Solubility
In Vitro:
DMSO : 125 mg/mL (505.70 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (271 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.0456 mL | 20.2282 mL | 40.4563 mL | 101.1409 mL |
| 5 mM | 0.8091 mL | 4.0456 mL | 8.0913 mL | 20.2282 mL | |
| 10 mM | 0.4046 mL | 2.0228 mL | 4.0456 mL | 10.1141 mL | |
| 15 mM | 0.2697 mL | 1.3485 mL | 2.6971 mL | 6.7427 mL | |
| 20 mM | 0.2023 mL | 1.0114 mL | 2.0228 mL | 5.0570 mL | |
| 25 mM | 0.1618 mL | 0.8091 mL | 1.6183 mL | 4.0456 mL | |
| 30 mM | 0.1349 mL | 0.6743 mL | 1.3485 mL | 3.3714 mL | |
| 40 mM | 0.1011 mL | 0.5057 mL | 1.0114 mL | 2.5285 mL | |
| 50 mM | 0.0809 mL | 0.4046 mL | 0.8091 mL | 2.0228 mL | |
| 60 mM | 0.0674 mL | 0.3371 mL | 0.6743 mL | 1.6857 mL | |
| 80 mM | 0.0506 mL | 0.2529 mL | 0.5057 mL | 1.2643 mL | |
| 100 mM | 0.0405 mL | 0.2023 mL | 0.4046 mL | 1.0114 mL |