1. Metabolic Enzyme/Protease
  2. Drug Metabolite
  3. 2-Methyl-tetrahydro-β-carboline

2-Methyl-tetrahydro-β-carboline  (Synonyms: 2-MTHBC)

Cat. No.: HY-W031110 Purity: 99.06%
Handling Instructions Technical Support

2-Methyl-tetrahydro-β-carboline is a cyclization product of N,N-dimethyltryptamine after oral administration of ayahuasca.

For research use only. We do not sell to patients.

2-Methyl-tetrahydro-β-carboline

2-Methyl-tetrahydro-β-carboline Chemical Structure

CAS No. : 13100-00-0

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Description

2-Methyl-tetrahydro-β-carboline is a cyclization product of N,N-dimethyltryptamine after oral administration of ayahuasca[1].

Molecular Weight

186.25

Formula

C12H14N2

CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

CN(C1)CCC2=C1NC3=C2C=CC=C3

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (268.46 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.3691 mL 26.8456 mL 53.6913 mL
5 mM 1.0738 mL 5.3691 mL 10.7383 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 5.3691 mL 26.8456 mL 53.6913 mL 134.2282 mL
5 mM 1.0738 mL 5.3691 mL 10.7383 mL 26.8456 mL
10 mM 0.5369 mL 2.6846 mL 5.3691 mL 13.4228 mL
15 mM 0.3579 mL 1.7897 mL 3.5794 mL 8.9485 mL
20 mM 0.2685 mL 1.3423 mL 2.6846 mL 6.7114 mL
25 mM 0.2148 mL 1.0738 mL 2.1477 mL 5.3691 mL
30 mM 0.1790 mL 0.8949 mL 1.7897 mL 4.4743 mL
40 mM 0.1342 mL 0.6711 mL 1.3423 mL 3.3557 mL
50 mM 0.1074 mL 0.5369 mL 1.0738 mL 2.6846 mL
60 mM 0.0895 mL 0.4474 mL 0.8949 mL 2.2371 mL
80 mM 0.0671 mL 0.3356 mL 0.6711 mL 1.6779 mL
100 mM 0.0537 mL 0.2685 mL 0.5369 mL 1.3423 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
2-Methyl-tetrahydro-β-carboline
Cat. No.:
HY-W031110
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