23S rRNA (adenosine1067-2'-O)-Methyltransferase

23S rRNA (adenosine-1067-2'-O)-methyltransferase (EC 2.1.1.230) is a methyltransferase that utilizes S-adenosylmethionine (SAM) as a methyl donor to methylate the 2'-hydroxyl group of the ribose at position A1067 of bacterial 23S rRNA, thereby conferring resistance to thiopeptide antibiotics.

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