2. Natural Products
  3. Plants Phenylpropanoids Phenols
  4. Anacardiaceae Simple Phenylpropanols Polyphenols
  5. Toxicodendron vernicifluum (Stokes) F. A. Barkl.
  6. 3-Heptadecylcatechol

3-Heptadecylcatechol is an urushiphenol compound found in Toxicodendron vernicifluum resin and poison oak urushiol. 3-Heptadecylcatechol exhibits anti-platelet aggregation and immune regulation activity. 3-Heptadecylcatechol can be used for the research of thrombotic disorders.

For research use only. We do not sell to patients.

3-Heptadecylcatechol

3-Heptadecylcatechol Chemical Structure

CAS No. : 5862-27-1

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3-Heptadecylcatechol Related Antibodies

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Description

3-Heptadecylcatechol is an urushiphenol compound found in Toxicodendron vernicifluum resin and poison oak urushiol. 3-Heptadecylcatechol exhibits anti-platelet aggregation and immune regulation activity. 3-Heptadecylcatechol can be used for the research of thrombotic disorders[1][2][3].

In Vitro

3-Heptadecylcatechol (5 min) inhibits ADP-induced rabbit platelet aggregation with an IC50 of 7.67 μmol/L and AA-induced rabbit platelet aggregation with an IC50 of 6.04 μmol/L[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

3-Heptadecylcatechol Related Antibodies
In Vivo

3-Heptadecylcatechol (50 μg-2.5 mg; cutaneous application; single dose) induces contact hypersensitivity in BALB/c mice[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: BALB/c mice (male or female, 6-10 weeks)[2]
Dosage: 2.5 mg (abdominal cutaneous application); 50 μg (ear cutaneous application)
Administration: cutaneous application; single dose
Result: Induced draining inguinal lymph node cell (LNC) proliferation that peaked 5-6 days post-abdominal treatment, while distal cervical LNC showed minimal proliferation.
Induced cervical LNC proliferation that peaked 5 days post-ear treatment; prior abdominal sensitization strongly suppressed this cervical LNC proliferation.
Induced suppressive activity against recipient LNC proliferation starting 7 days post-sensitization, with up to 58% suppression observed 10 days post-sensitization.
Showed both specific and non-specific components: suppression of homologous-induced proliferation was significantly stronger than suppression of OX-induced proliferation.
Completely abrogated suppressive activity when sensitized LNC were treated with anti-Thy-1.2 antibody plus complement, confirming suppressor cells are T lymphocytes.
Did not suppress the in vitro proliferation of optimally activated day-6 sensitized LNC.
Did not affect the induction of contact sensitivity, as ear swelling responses post-challenge were equivalent between recipients of sensitized LNC and normal LNC.
Molecular Weight

348.56

Formula

C23H40O2
CAS No.
SMILES

OC1=CC=CC(CCCCCCCCCCCCCCCCC)=C1O
Structure Classification
Initial Source
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Storage

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Purity & Documentation
References
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3-Heptadecylcatechol Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

3-Heptadecylcatechol5862-27-1Othersrabbit platelet aggregationcontact sensitivitydelayed-type hypersensitivitysuppressor T lymphocyteToxicodendron vernicifluumBALB/c micethrombotic disordersADP-induced aggregationAA-induced aggregationdraining lymph node cell proliferationInhibitorinhibitorinhibit

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