(3R)-7,4’-Dihydrohomoisoflavanone
Based on 1 Customer Validation
(3R)-7,4’-Dihydrohomoisoflavanone is a natural product with antibacterial activities against S. aureus and methicillin-resistant Staphylococcus aureus (MRSA).
For research use only. We do not sell to patients.
- Purity: 96.46%
- CAS No.: 1178893-64-5
- Formula: C16H14O4
- Molecular Weight:270.28
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
Description
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
>100 μM
Compound: 20
|
Cytotoxicity against human A549 cells after 72 hrs by MTT assay
Cytotoxicity against human A549 cells after 72 hrs by MTT assay
|
[PMID: 19689125] |
| B16-BL6 | IC50 |
99.6 μM
Compound: 20
|
Cytotoxicity against mouse B16-BL6 cells after 72 hrs by MTT assay
Cytotoxicity against mouse B16-BL6 cells after 72 hrs by MTT assay
|
[PMID: 19689125] |
| HeLa | IC50 |
>100 μM
Compound: 20
|
Cytotoxicity against human HeLa cells after 72 hrs by MTT assay
Cytotoxicity against human HeLa cells after 72 hrs by MTT assay
|
[PMID: 19689125] |
| HT-1080 | IC50 |
>100 μM
Compound: 20
|
Cytotoxicity against human HT1080 cells after 72 hrs by MTT assay
Cytotoxicity against human HT1080 cells after 72 hrs by MTT assay
|
[PMID: 19689125] |
In Vitro
(3R)-7,4’-Dihydrohomoisoflavanone shows cytotoxicity against K-562, SMMC-7721, and SGC-7901 cell lines with IC50 values of 15.6 μg/mL, 30.2 μg/mL, and 20.5 μg/mL, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1178893-64-5
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Appearance Solid
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Molecular Weight 270.28
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Formula C16H14O4
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Color White to off-white
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SMILES
O=C1[C@H](CC2=CC=C(O)C=C2)COC3=CC(O)=CC=C13
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Purity & Documentation
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Data Sheet (277 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)