4,2′,4′,6′-Tetramethoxychalcone
Based on 1 Customer Validation
4,2′,4′,6′-Tetramethoxychalcone is a flavonoids that can be isolated from Gnaphalium affine.
For research use only. We do not sell to patients.
- Purity: 99.51%
- CAS No.: 94103-36-3
- Formula: C19H20O5
- Molecular Weight:328.36
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
46.6 μM
Compound: 13b
|
Cytotoxicity against human A549 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
Cytotoxicity against human A549 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
|
[PMID: 25629304] |
| HeLa | IC50 |
19.6 μM
Compound: 13b
|
Cytotoxicity against human HeLa cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
Cytotoxicity against human HeLa cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
|
[PMID: 25629304] |
| HepG2 | IC50 |
13.5 μM
Compound: 13b
|
Cytotoxicity against human HepG2 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
Cytotoxicity against human HepG2 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
|
[PMID: 25629304] |
| RAW264.7 | IC50 |
15.2 μM
Compound: 12
|
Inhibition of LPS-induced nitric oxide production in mouse RAW264.7 cells
Inhibition of LPS-induced nitric oxide production in mouse RAW264.7 cells
|
[PMID: 17988874] |
Chemical Information
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CAS No. 94103-36-3
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Appearance Solid
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Molecular Weight 328.36
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Formula C19H20O5
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Color White to off-white
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SMILES
COC(C=C1)=CC=C1/C=C/C(C2=C(C=C(C=C2OC)OC)OC)=O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 50 mg/mL (152.27 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (267 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.0454 mL | 15.2272 mL | 30.4544 mL | 76.1360 mL |
| 5 mM | 0.6091 mL | 3.0454 mL | 6.0909 mL | 15.2272 mL | |
| 10 mM | 0.3045 mL | 1.5227 mL | 3.0454 mL | 7.6136 mL | |
| 15 mM | 0.2030 mL | 1.0151 mL | 2.0303 mL | 5.0757 mL | |
| 20 mM | 0.1523 mL | 0.7614 mL | 1.5227 mL | 3.8068 mL | |
| 25 mM | 0.1218 mL | 0.6091 mL | 1.2182 mL | 3.0454 mL | |
| 30 mM | 0.1015 mL | 0.5076 mL | 1.0151 mL | 2.5379 mL | |
| 40 mM | 0.0761 mL | 0.3807 mL | 0.7614 mL | 1.9034 mL | |
| 50 mM | 0.0609 mL | 0.3045 mL | 0.6091 mL | 1.5227 mL | |
| 60 mM | 0.0508 mL | 0.2538 mL | 0.5076 mL | 1.2689 mL | |
| 80 mM | 0.0381 mL | 0.1903 mL | 0.3807 mL | 0.9517 mL | |
| 100 mM | 0.0305 mL | 0.1523 mL | 0.3045 mL | 0.7614 mL |