4-Benzoyl-3-methyl-1-phenyl-5-pyrazolone
4-Benzoyl-3-methyl-1-phenyl-5-pyrazolone, is a heterocyclic compound with a five-membered ring structure, which can be used as a starting material for organic synthesis, a reagent for organic transformation, and a biological probe for studying biological processes. 4-Benzoyl-3-methyl-1-phenyl-5-pyrazolone is a biomaterial or organic compound that can be used as a research-related biomaterial or organic compound in life sciences.
For research use only. We do not sell to patients.
- Purity : 98.0%
- CAS No.: 4551-69-3
- Formula: C17H14N2O2
- Molecular Weight:278.31
-
Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
Description
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HUVEC | IC50 |
36.3 μg/mL
Compound: L2, HQPh
|
Antiinflammatory activity in HUVEC assessed as inhibition of TNF-alpha-induced cell surface ICAM1 expression preincubated before TNFalpha challenge measured after 16 hrs by ELISA
Antiinflammatory activity in HUVEC assessed as inhibition of TNF-alpha-induced cell surface ICAM1 expression preincubated before TNFalpha challenge measured after 16 hrs by ELISA
|
[PMID: 19674910] |
| N2a #58 F3 | IC50 |
1 μM
Compound: 18
|
Antiprion activity in F3 cells assessed as inhibition of protease-resistant prion protein accumulation
Antiprion activity in F3 cells assessed as inhibition of protease-resistant prion protein accumulation
|
[PMID: 17850126] |
| ScN2a | IC50 |
6 nM
Compound: 18
|
Antiprion activity in ScN2a cells assessed as inhibition of protease-resistant prion protein accumulation
Antiprion activity in ScN2a cells assessed as inhibition of protease-resistant prion protein accumulation
|
[PMID: 17850126] |
Chemical Information
-
CAS No. 4551-69-3
-
Appearance Solid
-
Molecular Weight 278.31
-
Formula C17H14N2O2
-
Color Off-white to yellow
-
SMILES
O=C(C1C(N(C2=CC=CC=C2)N=C1C)=O)C3=CC=CC=C3
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
-
Data Sheet (270 KB)
-
SDS (392 KB)
- English - EN (392 KB)
- Français - FR (392 KB)
- Deutsch - DE (392 KB)
- Norwegian - NO (392 KB)
- Español - ES (392 KB)
- Swedish - SV (392 KB)
- Italian - IT (392 KB)
- Korean - KR (392 KB)
- Portuguese - PT (392 KB)
-
Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
4-Benzoyl-3-methyl-1-phenyl-5-pyrazolone Related Classifications
HY-W011579 Related Classifications
Powered by Bioz