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Cat. No.: HY-N12907

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4′-Oxomacrophorin A

4′-Oxomacrophorin A is an immunosuppressant and can be isolated from Eupenicillium crustaceum.

For research use only. We do not sell to patients.

CAS No.: 349147-29-1
Formula: C₂₂H₃₀O₄
Molecular Weight:358.47

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

4′-Oxomacrophorin A Chemical Structure

CAS No.: 349147-29-1

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Bioz

Biological Activity

Description

4′-Oxomacrophorin A is an immunosuppressant and can be isolated from Eupenicillium crustaceum^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
T-cell	IC₅₀	0.5 μg/mL Compound: 2, EC-B	Immunosuppressant activity in mouse T cells assessed as inhibition of concanavalin A-induced cell proliferation Immunosuppressant activity in mouse T cells assessed as inhibition of concanavalin A-induced cell proliferation	[PMID: 11575965]

In Vitro

4′-Oxomacrophorin A inhibits Con A- and LPS-induced proliferation of mouse splenic lymphocyte with IC₅₀ values of 0.5 and 0.25 μg/mL, respectively^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 349147-29-1
Molecular Weight 358.47
Formula C₂₂H₃₀O₄
SMILES

O=C(C(CO)=CC1=O)[C@](O2)([H])[C@@]21C[C@@H]3[C@@]4([C@@](C(C)(CCC4)C)([H])CCC3=C)C
Structure Classification
- Others
Initial Source
- Microorganisms
Ascomycete Eupenicillium crustaceum
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Fujimoto H, et al. Immunomodulatory constituents from an Ascomycete, Eupenicillium crustaceum, and revised absolute structure of macrophorin D. J Nat Prod. 2001 Sep;64(9):1234-7. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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