2. Metabolic Enzyme/Protease
  3. Liposome
  4. 4A3-Cit

4A3-Cit is an ionizable lipid used for the generation of lipid nanoparticles (LNPs).

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

4A3-Cit

4A3-Cit 화학구조

CAS No. : 2768211-13-6

사이즈 가격 재고 수량
Oil + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 해외재고보유
Solution
10 mM * 1 mL in DMSO 해외재고보유
Oil
1 mg 해외재고보유
5 mg 해외재고보유
10 mg 해외재고보유
50 mg   견적 받기  
100 mg   견적 받기  

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

고객리뷰

Based on 1 publication(s) in Google Scholar

4A3-Cit Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE 4A3-Cit

  • Biological Activity

  • 순도&문서

  • References

  • 고객리뷰

제품 설명

4A3-Cit is an ionizable lipid used for the generation of lipid nanoparticles (LNPs).

In Vitro

4A3-Cit can undergo lipid fusion with endosomal membranes within the model, thereby facilitating endosomal escape. 4A3-Cit can enhance the efficiency of in vivo mRNA delivery through Selective Organ Targeting (SORT)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

4A3-Cit Related Antibodies
분자량

1571.33

화학식

C83H147N3O16S4
CAS No.
Appearance

Oil

Color

Colorless to light yellow

SMILES

O=C(CCN(CCCN(CCCN(CCC(OCCOC(C(CSCCC(CC/C=C(C)/C)C)C)=O)=O)CCC(OCCOC(C(CSCCC(CC/C=C(C)/C)C)C)=O)=O)C)CCC(OCCOC(C(CSCCC(CC/C=C(C)/C)C)C)=O)=O)OCCOC(C(CSCCC(CC/C=C(C)\C)C)C)=O
선적

Room temperature in continental US; may vary elsewhere.
보관
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
용액&용해도
In Vitro: 

DMSO : 100 mg/mL (63.64 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.6364 mL 3.1820 mL 6.3640 mL
5 mM 0.1273 mL 0.6364 mL 1.2728 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • 몰농도 계산기

  • 농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
순도&문서
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.6364 mL 3.1820 mL 6.3640 mL 15.9101 mL
5 mM 0.1273 mL 0.6364 mL 1.2728 mL 3.1820 mL
10 mM 0.0636 mL 0.3182 mL 0.6364 mL 1.5910 mL
15 mM 0.0424 mL 0.2121 mL 0.4243 mL 1.0607 mL
20 mM 0.0318 mL 0.1591 mL 0.3182 mL 0.7955 mL
25 mM 0.0255 mL 0.1273 mL 0.2546 mL 0.6364 mL
30 mM 0.0212 mL 0.1061 mL 0.2121 mL 0.5303 mL
40 mM 0.0159 mL 0.0796 mL 0.1591 mL 0.3978 mL
50 mM 0.0127 mL 0.0636 mL 0.1273 mL 0.3182 mL
60 mM 0.0106 mL 0.0530 mL 0.1061 mL 0.2652 mL
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4A3-Cit Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

4A3-Cit2768211-13-6LiposomeInhibitorinhibitorinhibit

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Inquiry Information

상품명:
4A3-Cit
Cat. No.:
HY-153373
수량:
MCE Japan Authorized Agent:

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