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(5R)-Carbapenem-3-carboxylate synthase

(5R)-Carbapenem-3-carboxylate synthase (EC 1.14.20.3) requires Fe2+. The enzyme is involved in the biosynthesis of the carbapenem β-lactam antibiotic (5R)-carbapen-2-em-3-carboxylate in the bacterium Pectobacterium carotovorum. (5R)-Carbapenem-3-carboxylate synthase (EC 1.14.20.3) catalyses a stereoinversion at C-5 and introduces a double bond between C-2 and C-3.

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  • (5R)-Carbapenem-3-carboxylate synthase Chemical Structure
    (5R)-Carbapenem-3-carboxylate synthase Chemical Structure
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    (5R)-Carbapenem-3-carboxylate synthase Chemical Structure
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  • (5R)-Carbapenem-3-carboxylate synthase