6-Amino-5-azacytidine
Based on 1 Customer Validation
6-Amino-5-azacytidine inhibits the growth of bacteria E. coli.
For research use only. We do not sell to patients.
- Purity: 95.0%
- CAS No.: 105331-00-8
- Formula: C8H13N5O5
- Molecular Weight:259.22
-
Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
Anti-bacteria (E. coli)[1]
6-Amino-5-azacytidine has an ID50 of 33.9 μM against CCRF-CEM cells and inhibits the growth of WI-L2 cells by 39% at 100 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 105331-00-8
-
Appearance Solid
-
Molecular Weight 259.22
-
Formula C8H13N5O5
-
Color White to off-white
-
SMILES
O=C1N([C@H]2[C@H](O)[C@H](O)[C@@H](CO)O2)C(N)=NC(N)=N1
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
H2O : 14.71 mg/mL (56.75 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
For the following dissolution methods, please prepare the working solution directly:
It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: PBS
Solubility: 8.33 mg/mL (32.13 mM); Clear solution; Need ultrasonic and warming and heat to 60°C
Purity & Documentation
-
Data Sheet (272 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 3.8577 mL | 19.2886 mL | 38.5773 mL | 96.4432 mL |
| 5 mM | 0.7715 mL | 3.8577 mL | 7.7155 mL | 19.2886 mL | |
| 10 mM | 0.3858 mL | 1.9289 mL | 3.8577 mL | 9.6443 mL | |
| 15 mM | 0.2572 mL | 1.2859 mL | 2.5718 mL | 6.4295 mL | |
| 20 mM | 0.1929 mL | 0.9644 mL | 1.9289 mL | 4.8222 mL | |
| 25 mM | 0.1543 mL | 0.7715 mL | 1.5431 mL | 3.8577 mL | |
| 30 mM | 0.1286 mL | 0.6430 mL | 1.2859 mL | 3.2148 mL | |
| 40 mM | 0.0964 mL | 0.4822 mL | 0.9644 mL | 2.4111 mL | |
| 50 mM | 0.0772 mL | 0.3858 mL | 0.7715 mL | 1.9289 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
6-Amino-5-azacytidine Related Classifications
HY-111643 Related Classifications
Powered by Bioz