8-Amino-1-octanol
Based on 1 Customer Validation
8-Amino-1-octanol (NH2-(CH2)7-COOH) is a PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 99.97%
- CAS No.: 19008-71-0
- Formula: C8H19NO
- Molecular Weight:145.25
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
All PROTAC Linkers Isoforms
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Biological Activity
Description
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E458 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 19008-71-0
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Appearance Solid
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Molecular Weight 145.25
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Formula C8H19NO
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Color Off-white to yellow
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SMILES
OCCCCCCCCN
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Synonyms
NH2-(CH2)7-COOH
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
In Vitro:
DMSO : 50 mg/mL (344.23 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (237 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 6.8847 mL | 34.4234 mL | 68.8468 mL | 172.1170 mL |
| 5 mM | 1.3769 mL | 6.8847 mL | 13.7694 mL | 34.4234 mL | |
| 10 mM | 0.6885 mL | 3.4423 mL | 6.8847 mL | 17.2117 mL | |
| 15 mM | 0.4590 mL | 2.2949 mL | 4.5898 mL | 11.4745 mL | |
| 20 mM | 0.3442 mL | 1.7212 mL | 3.4423 mL | 8.6059 mL | |
| 25 mM | 0.2754 mL | 1.3769 mL | 2.7539 mL | 6.8847 mL | |
| 30 mM | 0.2295 mL | 1.1474 mL | 2.2949 mL | 5.7372 mL | |
| 40 mM | 0.1721 mL | 0.8606 mL | 1.7212 mL | 4.3029 mL | |
| 50 mM | 0.1377 mL | 0.6885 mL | 1.3769 mL | 3.4423 mL | |
| 60 mM | 0.1147 mL | 0.5737 mL | 1.1474 mL | 2.8686 mL | |
| 80 mM | 0.0861 mL | 0.4303 mL | 0.8606 mL | 2.1515 mL | |
| 100 mM | 0.0688 mL | 0.3442 mL | 0.6885 mL | 1.7212 mL |
8-Amino-1-octanol Related Classifications
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