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Cat. No.: HY-111782R

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8-Mercaptoguanosine (Standard)

Name: 8-Mercaptoguanosine (Standard)
Brand: MedChemExpress
SKU: HY-111782R
Availability: PreOrder

(Synonyms: 8-Thioguanosine (Standard))

8-Mercaptoguanosine (Standard) is the analytical standard of 8-Mercaptoguanosine (HY-111782). This product is intended for research and analytical applications. 8-Mercaptoguanosine is an immunoadjuvant that affects the in vivo antibody response to the T-cell-independent antigen TNP-Ficoll. 8-Mercaptoguanosine enhances IgG1, IgG2, and IgG3 antibody responses, but has no effect on IgM antibody responses. 8-Mercaptoguanosine also enhances antibody responses to very weak antigens such as pneumococcal polysaccharide and restores antibody responses in immunodeficient xid mice that are non-reactive to TNP-Ficoll.

For research use only. We do not sell to patients.

CAS No.: 26001-38-7
Formula: C₁₀H₁₃N₅O₅S
Molecular Weight:315.31

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

8-Mercaptoguanosine (Standard) Chemical Structure

CAS No.: 26001-38-7

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Product Information

Information

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 26001-38-7
Molecular Weight 315.31
Formula C₁₀H₁₃N₅O₅S
SMILES

NC(NC1=O)=NC2=C1NC(N2[C@H]3[C@H](O)[C@H](O)[C@@H](CO)O3)=S
Synonyms

8-Thioguanosine (Standard)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Mond JJ, Hunter K, Kenny JJ, Finkelman F, Witherspoon K. 8-Mercaptoguanosine-mediated enhancement of in vivo IgG1, IgG2 and IgG3 antibody responses to polysaccharide antigens in normal and xid mice. Immunopharmacology. 1989 Nov-Dec;18(3):205-12. [Content Brief]

[2]. Feldbush TL, Ballas ZK. Lymphokine-like activity of 8-mercaptoguanosine: induction of T and B cell differentiation. J Immunol. 1985 May;134(5):3204-11. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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