Dot1L-IN-1

Dot1L-IN-1 is a highly potent and selective Dot1L inhibitor with a Ki of 2 pM and an IC50 of <0.1 nM. Dot1L-IN-1 potently suppresses H3K79 dimethylation (IC50=3 nM), as well as the activity of the HoxA9 promoter (IC50=17 nM) in HeLa and Molm-13 cells, respectively.

For research use only. We do not sell to patients.

  • CAS No.: 2088518-50-5
  • Formula: C32H36ClN9O2S
  • Molecular Weight:646.21
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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