1. Peptides

Leucokinin VIII (Synonyms: Leucokinin 8)

Cat. No.: HY-P1496
Handling Instructions

Leucokinin VIII is an diuretic octapeptide isolated form head extracts of the cockroach. Sequence: Gly-Ala-Ser-Phe-Tyr-Ser-Trp-Gly-NH2;GASFYSWG-NH2.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Leucokinin VIII Chemical Structure

Leucokinin VIII Chemical Structure

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Customer Review

  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

Leucokinin VIII is an diuretic octapeptide isolated form head extracts of the cockroach. Sequence: Gly-Ala-Ser-Phe-Tyr-Ser-Trp-Gly-NH2;GASFYSWG-NH2.

In Vitro

Leucokinin VIII is an octapeptide, increases the rates of transepithelial NaC1, KC1 and water secretion, increases the Cl conductance of the epithelial shunt via a receptor located at the basolateral side of the epithelium[1]. Leucokinin VIII also activates Ca2+-dependent signal pathway in principal cells of Aedes aegyptiMalpighian tubules[2].

Solvent & Solubility
In Vitro: 

H2O

Peptide Solubility and Storage Guidelines:

1.  Calculate the length of the peptide.

2.  Calculate the overall charge of the entire peptide according to the following table:

  Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.  Recommended solution:

Overall charge of peptide Details
Negative (<0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, add NH4OH (<50 μL).
3.  If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (>0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.  If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.  Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.  For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
References
Molecular Weight

872.92

Formula

C₄₂H₅₂N₁₀O₁₁

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Inquiry Information

Product Name:
Leucokinin VIII
Cat. No.:
HY-P1496
Quantity:

Leucokinin VIII

Cat. No.: HY-P1496