Huperziaceae

(-)-Huperzine A (Huperzine A) is an alkaloid isolated from Huperzia serrata, with neuroprotective activity. (-)-Huperzine A is a potent, highly specific, reversible and blood-brain barrier penetrant inhibitor of acetylcholinesterase (AChE), with an IC₅₀ of 82 nM. (-)-Huperzine A also is non-competitive antagonist of N-methyl-D-aspartate glutamate (NMDA) receptor. (-)-Huperzine A is developed for the research of neurodegenerative diseases, including Alzheimer’s disease.

(±)-Huperzine A is the racemate of (-)-Huperzine A (HY-17387). (-)-Huperzine A is an alkaloid isolated from Huperzia serrata, with neuroprotective activity. (-)-Huperzine A is a potent, highly specific, reversible and blood-brain barrier penetrant inhibitor of acetylcholinesterase (AChE), with an IC₅₀ of 82 nM. (-)-Huperzine A also is non-competitive antagonist of N-methyl-D-aspartate glutamate (NMDA) receptor. (-)-Huperzine A is developed for the research of neurodegenerative diseases, including Alzheimer’s disease.

5-Methylhydantoin is a hydantoin derivative, can be used in the synthesis of several pharmaceutical drugs.

3β-Acetoxylanosta-7,9 (11),24-trien-21-oic acid is a lanostane-type triterpenoid that is isolated from the culture broth of Ceriporia lacerata HS-ZJUT-C13A, an endophytic fungus residing in the stems of the medicinal plant Huperzia serrata. 3β-Acetoxylanosta-7,9 (11),24-trien-21-oic acid is applicable to studies on lanostane-type triterpenoids and fungus-derived natural products.

3-O-Dihydro-p-coumaroyltohogenol is a PTP1B inhibitor (IC₅₀=6.27 μM) with antidiabetic and antiobesity activities.

6α-Hydroxylycopodine (Alkaloid L20) is a Flavonoids product that can be isolated from the herbs of Crotalaria barbata.