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Cat. No.: HY-N13199

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3-O-Dihydro-p-coumaroyltohogenol

3-O-Dihydro-p-coumaroyltohogenol is a PTP1B inhibitor (IC₅₀=6.27 μM) with antidiabetic and antiobesity activities.

For research use only. We do not sell to patients.

Formula: C₃₉H₆₀O₅
Molecular Weight:608.89

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

3-O-Dihydro-p-coumaroyltohogenol Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

3-O-Dihydro-p-coumaroyltohogenol is a PTP1B inhibitor (IC₅₀=6.27 μM) with antidiabetic and antiobesity activities^[1].

Chemical Information

Molecular Weight 608.89
Formula C₃₉H₆₀O₅
SMILES

CC1(C)[C@]2([H])CC[C@]3(O)C[C@]4(C)CC[C@@]5([H])C(C)(C)[C@@H](OC(CCC6=CC=C(O)C=C6)=O)CC[C@]5(C)[C@@]4([H])CCC3[C@@]2(C)CC[C@@H]1O
Structure Classification
- Terpenoids
- Triterpenes
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Ryu, et al. "Inhibition of protein tyrosine phosphatase 1B by serratane triterpenes from Huperzia serrata and their molecular docking study." Bioorganic & Medicinal Chemistry Letters 111 (2024): 129904. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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