2. Signaling Pathways
  3. Apoptosis
    Autophagy
  4. 14-3-3 Protein
  5. 14-3-3ζ Isoform
  6. 14-3-3ζ Modulator

14-3-3ζ Modulator

14-3-3ζ Modulator (1):

Cat. No. Product Name Effect Purity
  • HY-179576
    CV2a
    		Modulator
    CV2a is a 14-3-3-directed molecular glue-based PROTAC that selectively targets the ERα protein complex with an EC50 of 0.10 μM. CV2a cooperatively recruits VHL to the 14-3-3/ERα complex and promotes robust polyubiquitination of the 14-3-3ζ/ERα complex.