2. Signaling Pathways
  3. Apoptosis
    Autophagy
  4. 14-3-3 Protein
  5. 14-3-3ζ Isoform

14-3-3ζ

 

14-3-3ζ Related Products (3):

Cat. No. Product Name Effect Purity
  • HY-171977
    UTKO1
    		Inhibitor
    UTKO1 (Compound 2) is a derivate of Moverastin.UTKO1 has optical activity and significant inhibitory activity against tumor cell migration by abrogating the binding of 14-3-3ζ/Tiam1. UTKO1 can be used for cancers like esophageal cancer and epidermoid carcinoma research.
  • HY-179576
    CV2a
    		Modulator
    CV2a is a 14-3-3-directed molecular glue-based PROTAC that selectively targets the ERα protein complex with an EC50 of 0.10 μM. CV2a cooperatively recruits VHL to the 14-3-3/ERα complex and promotes robust polyubiquitination of the 14-3-3ζ/ERα complex.
  • HY-162838
    TCF199
    		Inducer
    TCF199 is an allosteric stabilizer that stabilizes the 14-3-3/TAZ peptide interaction, binding to the 14-3-3ζ/E R α peptide and 14-3-3ζ/Chibby peptide. TCF199 has a Kd value of 122 μM for its interaction with 14-3-3/TAZ.