2. Signaling Pathways
  3. Stem Cell/Wnt
  4. Hippo (MST)
  5. MST2 Isoform
  6. MST2 Inhibitor

MST2 Inhibitor

MST2 Inhibitors (2):

Cat. No. Product Name Effect Purity
  • HY-132969
    SBP-3264
    		Inhibitor 98.50%
    SBP-3264 is a YAP activator and STK/MST inhibitor with IC50 values of 36 nM against STK3/MST2 and 24 nM against STK4/MST1. SBP-3264 modulates the Hippo signaling pathway. SBP-3264 can be used for the research of acute myeloid leukemia.
  • HY-164595
    IHMT-MST1-39
    		Inhibitor 99.68%
    IHMT-MST1-39 is an orally active inhibitor for MST kinase, with IC50 of 42, 109, 286, 159 nM for MST1, MST2, MST3, MST4. IHMT-MST1-39 activates the AMPK signaling pathway in liver cells, reduces apoptosis of pancreatic β-cells. IHMT-MST1-39 can be used for the studies of type 1 diabetes (T1D) and type 2 diabetes (T2D).