Coccidia
Coccidia comprise protozoan parasites including Toxoplasma gondii, Neospora caninum, Eimeria spp., and Cystoisospora spp., and their life cycle switches between asexual and sexual stages[1]. Mechanistically, Eimeria invasion depends on coccidian organelles and host-cell interaction during intestinal infection[2][3]. In poultry models, Eimeria invades the intestinal tract and causes coccidiosis, with disease severity and lesions varying by parasite species[4][3]. Compared with T. gondii, which infects warm-blooded animals asexually but restricts sexual development to felines, Eimeria usually completes its whole life cycle in one host species[5]. For experimental applications, monolayer cultures, organoids, axenic systems, and host cell-free Cystoisospora suis models support research on parasite development, invasion, host-parasite interaction, and anticoccidial drug targets[1][6].
References:
- [1]. Feix AS, et al. In vitro cultivation methods for coccidian parasite research. Int J Parasitol. 2023 Aug;53(9):477-489. [Content Brief]
- [2]. Burrell A, et al. Life cycle stages, specific organelles and invasion mechanisms of Eimeria species. Parasitology. 2020 Mar;147(3):263-278. [Content Brief]
- [3]. López-Osorio S, et al. Overview of Poultry Eimeria Life Cycle and Host-Parasite Interactions. Front Vet Sci. 2020 Jul 3;7:384. [Content Brief]
- [4]. Mesa-Pineda C, et al. Chicken Coccidiosis: From the Parasite Lifecycle to Control of the Disease. Front Vet Sci. 2021 Dec 21;8:787653. [Content Brief]
- [5]. Martorelli Di Genova B, et al. Comparisons of the Sexual Cycles for the Coccidian Parasites Eimeria and Toxoplasma. Front Cell Infect Microbiol. 2020 Dec 14;10:604897. [Content Brief]
- [6]. Feix AS, et al. Progression of asexual to sexual stages of Cystoisospora suis in a host cell-free environment as a model for Coccidia. Parasitology. 2021 Oct;148(12):1475-1481. [Content Brief]
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Coccidia Related Products (27)
Related Products (27)
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Sulfaquinoxaline-d4
0 ImagesCat. No.: HY-B1282SCAS No.: 1329652-02-9Sulfaquinoxaline-d4 is the deuterium labeled Sulfaquinoxaline. Sulfaquinoxaline is an antimicrobial for veterinary use, with activity against a broad spectrum of Gram-negative and Gram-positive bacteria. Sulfaquinoxaline is used to prevent coccidiosis and bacterial infections.
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Clazuril
0 ImagesCat. No.: HY-101000CAS No.: 101831-36-1Synonyms: R62690Clazuril (R62690) has a coccidiocidal effect on the asexual and sexual developmental stages of both Eimeria species, resulting in a complete interruption of the life cycle.
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Nequinate
0 ImagesCat. No.: HY-116433CAS No.: 13997-19-8Nequinate, a quinoline compound, is an anticoccidial agent against cecal coccidiosis (Eimeria tenella) infections. Nequinate inhibits xanthine oxidoreductase (XOD) activity.
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Anticoccidial agent-1
0 ImagesCat. No.: HY-183528CAS No.: 762172-81-6Anticoccidial agent-1 is an imidazopyridine anticoccidial agent with an IC50 of 0.044. Anticoccidial agent-1 can be used for the research of coccidiosis.
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Sulfadimethoxine 1000 µg/mL in methanol
0 ImagesSulfadimethoxine (Sulphadimethoxine) 1000 µg/mL in methanol is an orally active sulfonamide antibiotic. Sulfadimethoxine 1000 µg/mL in methanol reduces Eimeria-related mortality, weight loss, and lesions. Sulfadimethoxine 1000 µg/mL in methanol can be used for the research of avian coccidiosis.
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