TNFRSF10B/DR5/CD262 Agonist
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Aplitabart
0 ImagesCat. No.: HY-P990901CAS No.: 2796349-94-3Synonyms: IGM-8444Aplitabart (IGM-8444) is a pentameric IgM death receptor 5 (DR5) agonist antibody with a KD of 85 nM and an apparent affinity of 11 pM. Aplitabart induces DR5 multimerization, thereby triggering cancer cell apoptosis via the extrinsic apoptotic pathway apoptosis. Aplitabart is applicable to cancer-related research such as colorectal cancer and gastric cancer.
