A2G2S2 glycan (G2S2)
A2G2S2 glycan (G2S2) (A2G2S2 N-linked oligosaccharide; A2G (4) 2S (6) 2 glycan) is a sialylated biantennary N-linked oligosaccharide that acts as a multifunctional fluorescent linker. The resulting conjugate exhibits high sensitivity and specificity by mimicking the antennal elements of N-glycans.
For research use only. We do not sell to patients.
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
The A2G2S2 glycan (G2S2) accounts for 2-5% of the total N-glycan subtypes on recombinant Trastuzumab (HY-P9907) expressed by CHO cells[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Synonyms
A2G2S2 N-linked oligosaccharide; A2G(4)2S(6)2 glycan
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Jiménez-Castells C, et al. Development of a multifunctional aminoxy-based fluorescent linker for glycan immobilization and analysis. Glycobiology. 2016 Dec;26(12):1297-1307. [Content Brief]
[2]. van Geel R, et al. Chemoenzymatic Conjugation of Toxic Payloads to the Globally Conserved N-Glycan of Native mAbs Provides Homogeneous and Highly Efficacious Antibody-Drug Conjugates. Bioconjugate chemistry. 2015 Nov 18;26(11):2233-42. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
A2G2S2 glycan (G2S2) Related Classifications
HY-158506 Related Classifications
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Keywords
- A2G2S2 glycan (G2S2)
- A2G2S2 N-linked oligosaccharide
- A2G(4)2S(6)2 glycan
- Biochemical Assay Reagents
- α2,3-sialic acid
- wheat germ agglutinin
- sialylated biantennary N-linked oligosaccharide
- A2G2S2 glycan
- Maackia amurensis agglutinin II
- α2,6-sialic acid
- β-galactose
- Ricinus communis agglutinin I
- CHO cells
- Sambucus nigra agglutinin
- Inhibitor
- inhibitor
- inhibit