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  2. Bacterial
  3. AHL modulator-1

AHL modulator-1 is a N-acylated L-homoserine lactone (AHL) modulator that modulating bacteria quorum sensing (QS). AHL modulator-1 can be used for the research of plant soft rot.

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AHL modulator-1

AHL modulator-1 화학구조

CAS No. : 942296-18-6

사이즈 가격 재고 수량
5 mg 해외재고보유
10 mg 해외재고보유
25 mg 해외재고보유
50 mg 해외재고보유
100 mg   견적 받기  
200 mg   견적 받기  

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제품 설명

AHL modulator-1 is a N-acylated L-homoserine lactone (AHL) modulator that modulating bacteria quorum sensing (QS). AHL modulator-1 can be used for the research of plant soft rot[1].

In Vitro

AHL modulator-1 (Compound 12) (5-200 μM) acts as a partial agonist and moderate antagonist of QS-regulated cellulase in Pectobacterium carotovora (ΔexpI), with 21% agonism at 200 μM and 42% antagonism at 5 μM[1].
AHL modulator-1 (50 μM) acts as a weak agonist and moderate antagonist of QS-regulated potato maceration by Pectobacterium carotovora (ΔexpI), with 5% agonism at 50 μM and 32% antagonism at 50 μM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

분자량

298.13

화학식

C12H12BrNO3

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

BrC(C=CC=C1)=C1CC(N[C@@H]2C(OCC2)=O)=O

선적

Room temperature in continental US; may vary elsewhere.

보관
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
용액&용해도
In Vitro: 

DMSO : 125 mg/mL (419.28 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.3542 mL 16.7712 mL 33.5424 mL
5 mM 0.6708 mL 3.3542 mL 6.7085 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Volume
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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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순도&문서
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.3542 mL 16.7712 mL 33.5424 mL 83.8560 mL
5 mM 0.6708 mL 3.3542 mL 6.7085 mL 16.7712 mL
10 mM 0.3354 mL 1.6771 mL 3.3542 mL 8.3856 mL
15 mM 0.2236 mL 1.1181 mL 2.2362 mL 5.5904 mL
20 mM 0.1677 mL 0.8386 mL 1.6771 mL 4.1928 mL
25 mM 0.1342 mL 0.6708 mL 1.3417 mL 3.3542 mL
30 mM 0.1118 mL 0.5590 mL 1.1181 mL 2.7952 mL
40 mM 0.0839 mL 0.4193 mL 0.8386 mL 2.0964 mL
50 mM 0.0671 mL 0.3354 mL 0.6708 mL 1.6771 mL
60 mM 0.0559 mL 0.2795 mL 0.5590 mL 1.3976 mL
80 mM 0.0419 mL 0.2096 mL 0.4193 mL 1.0482 mL
100 mM 0.0335 mL 0.1677 mL 0.3354 mL 0.8386 mL
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

상품명:
AHL modulator-1
Cat. No.:
HY-164128
수량:
MCE Japan Authorized Agent: