Amino-PEG2-CH2CH2-SH hydrochloride
Based on 1 Customer Validation
Amino-PEG2-CH2CH2-SH (hydrochloride) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 96.16%
- CAS No.: 3037676-58-4
- Formula: C6H16ClNO2S
- Molecular Weight:201.71
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Storage:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
All PROTAC Linkers Isoforms
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Biological Activity
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3037676-58-4
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Appearance Liquid
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Molecular Weight 201.71
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Formula C6H16ClNO2S
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Color Colorless to light yellow
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SMILES
[H]Cl.NCCOCCOCCS
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : 125 mg/mL (619.70 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (267 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.9576 mL | 24.7881 mL | 49.5761 mL | 123.9403 mL |
| 5 mM | 0.9915 mL | 4.9576 mL | 9.9152 mL | 24.7881 mL | |
| 10 mM | 0.4958 mL | 2.4788 mL | 4.9576 mL | 12.3940 mL | |
| 15 mM | 0.3305 mL | 1.6525 mL | 3.3051 mL | 8.2627 mL | |
| 20 mM | 0.2479 mL | 1.2394 mL | 2.4788 mL | 6.1970 mL | |
| 25 mM | 0.1983 mL | 0.9915 mL | 1.9830 mL | 4.9576 mL | |
| 30 mM | 0.1653 mL | 0.8263 mL | 1.6525 mL | 4.1313 mL | |
| 40 mM | 0.1239 mL | 0.6197 mL | 1.2394 mL | 3.0985 mL | |
| 50 mM | 0.0992 mL | 0.4958 mL | 0.9915 mL | 2.4788 mL | |
| 60 mM | 0.0826 mL | 0.4131 mL | 0.8263 mL | 2.0657 mL | |
| 80 mM | 0.0620 mL | 0.3099 mL | 0.6197 mL | 1.5493 mL | |
| 100 mM | 0.0496 mL | 0.2479 mL | 0.4958 mL | 1.2394 mL |