Aminooxy-PEG3-bromide hydrobromide
Based on 1 Customer Validation
Aminooxy-PEG3-bromide hydrobromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 2988654-05-1
- Formula: C8H19Br2NO4
- Molecular Weight:353.05
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Storage:
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
All PROTAC Linkers Isoforms
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Biological Activity
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2988654-05-1
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Appearance Oil
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Molecular Weight 353.05
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Formula C8H19Br2NO4
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Color Light yellow to yellow
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SMILES
NOCCOCCOCCOCCBr.Br
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvent & Solubility
DMSO : 250 mg/mL (708.11 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (266 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.8325 mL | 14.1623 mL | 28.3246 mL | 70.8115 mL |
| 5 mM | 0.5665 mL | 2.8325 mL | 5.6649 mL | 14.1623 mL | |
| 10 mM | 0.2832 mL | 1.4162 mL | 2.8325 mL | 7.0812 mL | |
| 15 mM | 0.1888 mL | 0.9442 mL | 1.8883 mL | 4.7208 mL | |
| 20 mM | 0.1416 mL | 0.7081 mL | 1.4162 mL | 3.5406 mL | |
| 25 mM | 0.1133 mL | 0.5665 mL | 1.1330 mL | 2.8325 mL | |
| 30 mM | 0.0944 mL | 0.4721 mL | 0.9442 mL | 2.3604 mL | |
| 40 mM | 0.0708 mL | 0.3541 mL | 0.7081 mL | 1.7703 mL | |
| 50 mM | 0.0566 mL | 0.2832 mL | 0.5665 mL | 1.4162 mL | |
| 60 mM | 0.0472 mL | 0.2360 mL | 0.4721 mL | 1.1802 mL | |
| 80 mM | 0.0354 mL | 0.1770 mL | 0.3541 mL | 0.8851 mL | |
| 100 mM | 0.0283 mL | 0.1416 mL | 0.2832 mL | 0.7081 mL |