Androgen receptor antagonist 4
Androgen receptor antagonist 4 (Compound AT2) is an androgen receptor (AR) antagonist with an IC50 of 0.15 μM. Androgen receptor antagonist 4 efficiently antagonizes AR transcriptional activity, suppresses downstream target gene of AR, and blocks the DHT-induced AR nuclear translocation. Androgen receptor antagonist 4 shows anticancer activities.
For research use only. We do not sell to patients.
- CAS No.: 354815-43-3
- Formula: C22H18ClN
- Molecular Weight:331.84
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
IC50: 0.15 μM (Androgen receptor)[1]
Chemical Information
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CAS No. 354815-43-3
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Molecular Weight 331.84
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Formula C22H18ClN
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SMILES
ClC1=CC=C(C2NC3=C(C4=CC=CC=C4C=C3)C5C2CC=C5)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Androgen receptor antagonist 4 Related Classifications
HY-146027 Related Classifications
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