Anti-Mouse/Human KLRG-1 Antibody (2F1) 

Anti-Mouse/Human KLRG-1 Antibody (2F1) is a Syrian hamster-derived IgG type antibody inhibitor, targeting to mouse/human KLRG-1. Anti-Mouse/Human KLRG-1 Antibody (2F1) neutralizes KLRG1. Anti-Mouse/Human KLRG-1 Antibody (2F1) reduces T-cell receptor signals and regulatory T-cell accumulation. Anti-Mouse/Human KLRG-1 Antibody (2F1) can be used for the researches of immunology^[1][2].

Syrian hamster IgG

Syrian Hamster IgG, Isotype Control

Human/Mouse

KLRG-1

Anti-Mouse/Human KLRG-1 Antibody (2F1) (5 μg/mL, 8 h or 3 days) reduces T-cell receptor signals and regulatory T-cell accumulation^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Anti-Mouse/Human KLRG-1 Antibody (2F1) (10 mg/kg, i.p., at day 0, 7, 14 and 21) neutralizes KLRG1 in WT or Rag1^–/– mice^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

50928  [NCBI]

O88713

Flow Cytometry

Unconjugated

The product can be reconstituted/diluted with sterile PBS or saline.

150 kDa

Liquid

Colorless to light yellow

[Anti-Mouse/Human KLRG-1 Antibody (2F1)]

Please refer to the lot-specific COA for specific buffer information.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Meinicke H, et al. KLRG1 impairs regulatory T-cell competitive fitness in the gut. Immunology. 2017 Sep;152(1):65-73.  [Content Brief]

  [2]. Bao K, et al. TCF-1 and TOX regulate the memory formation of intestinal group 2 innate lymphoid cells in asthma. Nat Commun. 2024 Sep 8;15(1):7850.  [Content Brief]