Anti-SARS-CoV-2 Spike mAb (CR3022)
Based on 1 Customer Validation
Anti-SARS-CoV-2 Spike mAb (CR3022) is a a CHO cell derived human monoclonal IgG1 antibody. It binds to both S1 domain of SARS-CoV/SARS-CoV-2 Spike protein.
For research use only. We do not sell to patients.
- Purity : ≥95.0%
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
CR3022 recognizes a cryptic epitope that is only accessible when S protein is in "open" conformations[1].
CR3022 binds more tightly to SARS-CoV because its epitope contains a glycan not present in SARS-CoV-2[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Conjugated
Unconjugated
Reconsititution
The product can be reconstituted/diluted with sterile PBS or saline.
Format
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Product Image
Application
ELISA, FACS, Functional assay
Chemical Information
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Appearance Liquid
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Color Colorless to light yellow
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SMILES
[Anti-SARS-CoV-2 Spike mAb (CR3022)]
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Synonyms
SARS-CR3022; SARS-CoV-2 Antibody-CR3022
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Shipping
Shipping with dry ice.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Data Sheet (256 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Inhibitory Antibodies User Guide (603 KB)
References
[1]. Yanling Wu, et al. Identification of Human Single-Domain Antibodies Against SARS-CoV-2. Cell Host Microbe. 2020 Jun 10;27(6):891-898.e5. [Content Brief]
[2]. Meng Yuan, et al. A Highly Conserved Cryptic Epitope in the Receptor Binding Domains of SARS-CoV-2 and SARS-CoV. Science. 2020 May 8;368(6491):630-633. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Anti-SARS-CoV-2 Spike mAb (CR3022) Related Classifications
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