2. Anti-infection
  3. Bacterial
  4. Antibacterial agent 12

Antibacterial agent 12, a biaryloxazolidinone analogue, is an antibacterial agent against antibiotic-susceptible and antibiotic-resistant Gram-positive bacteria.

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Antibacterial agent 12

Antibacterial agent 12 Estructura química

No. CAS : 2382921-99-3

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Antibacterial agent 12 Related Antibodies

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Descripciòn

Antibacterial agent 12, a biaryloxazolidinone analogue, is an antibacterial agent against antibiotic-susceptible and antibiotic-resistant Gram-positive bacteria[1].

Cellular Effect
Cell Line Type Value Description References
HepG2 IC50
>25 μM
Compound: 14a-7
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
[PMID: 31654879]
In Vitro

Antibacterial agent 12 (compound 14a-7) exhibits a MIC value of 0.125 μg/mL against S.aureus[1].
Antibacterial agent 12 (compound 14a-7) is stable in human liver microsome. Antibacterial agent 12 exhibits lower inhibitory activity against human MAO-A compared to Linezolid[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Antibacterial agent 12 Related Antibodies
Peso molecular

489.52

Fòrmula

C22H24FN5O5S
No. CAS
SMILES

CC(NC[C@H]1CN(C2=CC=C(C3=CC=C(/C=N/N4CCS(CC4)(=O)=O)N=C3)C(F)=C2)C(O1)=O)=O
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

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Referencias
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Antibacterial agent 12 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antibacterial agent 122382921-99-3Antibacterial agent12Antibacterial agent-12Bacterialantibacterial activityGram-positive bacteria,Inhibitorinhibitorinhibit

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Nombre del producto:
Antibacterial agent 12
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HY-126629
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