ABHD5 Antibody (YA1108)(PBS only)
(Synonyms: ABHD5; Abhydrolase domain containing 5; CDS; CGI58; IECN2; NCIE2)ABHD5 Antibody (YA1108) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ABHD5.
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Host:
Rabbit
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Isotype:
IgG
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Application:
IHC-P
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Reactivity :
Human
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Formulation:
Supplied in PBS, pH 7.4.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|
| Dilution Ratio | 1:100-1:200 |
Product Details
ABHD5 Antibody (YA1108) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ABHD5.
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Host Rabbit
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 45 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 39 kDa
A synthesized peptide derived from human ABHD5
Affinity Purified
Non-conjugated
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS, pH 7.4.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
ABHD5 is a Coenzyme A-dependent lysophosphatidic acid acyltransferase that catalyzes the transfer of an acyl group on a lysophosphatidic acid. Functions preferentially with 1-oleoyl-lysophosphatidic acid followed by 1-palmitoyl-lysophosphatidic acid, 1-stearoyl-lysophosphatidic acid and 1-arachidonoyl-lysophosphatidic acid as lipid acceptor. Functions preferentially with arachidonoyl-CoA followed by oleoyl-CoA as acyl group donors. Functions in phosphatidic acid biosynthesis. May regulate the cellular storage of triacylglycerol through activation of the phospholipase PNPLA2. Involved in keratinocyte differentiation. Regulates lipid droplet fusion[1][2][3].
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Subcellular Localization
Cytoplasm; Lipid droplet; Cytoplasm, cytosol
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Expression
Tissue_specificity:Widely expressed in various tissues, including lymphocytes, liver, skeletal muscle and brain. Expressed by upper epidermal layers and dermal fibroblasts in skin, hepatocytes and neurons (at protein level)
Induction:Up-regulated upon keratinocyte differentiation (at protein level) -
Subunit
Interacts with ADRP, PLIN and PNPLA2. Interacts with PLIN5; promotes interaction with PNPLA2 (By similarity)
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SwissProt ID
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Synonyms
ABHD5; Abhydrolase domain containing 5; CDS; CGI58; IECN2; NCIE2
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Research Field
Cardiovascular
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