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Cat. No.: HY-P87478

ADAM22 Antibody (YA7165)

ADAM22 Antibody (YA7165) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to ADAM22.

For research use only. We do not sell to patients.

Formulation:
Supplied in 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Applications

Application	WB WB: Western Blot
Dilution Ratio	1:500-2000

Description

ADAM22 Antibody (YA7165) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to ADAM22.

Immunogen

Recombinant human ADAM22 protein

Sensitivity

Endogenous

Purification

affinity purified by Protein A

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

Appearance

Liquid
Formulation

Supplied in 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.

Function

ADAM22 is a Probable ligand for integrin in the brain. This is a non catalytic metalloprotease-like protein. Involved in regulation of cell adhesion and spreading and in inhibition of cell proliferation. Neuronal receptor for LGI1^[1].
Subcellular Localization

Cell membrane,Cell projection, axon
Expression

Tissue_Specificity: Highly expressed in the brain and in some high-grade but not low-grade gliomas. Detected slightly or not at all in other tissues
Isoforms & Post-Translational Modification

Q9P0K1 has 5 isomers: Q9P0K1-1: 100433 Da (predicted); Q9P0K1-2: 100269 Da (predicted); Q9P0K1-3: 95288 Da (predicted); Q9P0K1-4: 91492 Da (predicted); Q9P0K1-5: 96637 Da (predicted).
The precursor is cleaved by a furin endopeptidase
Subunit

Interacts with LGI1 (PubMed:27066583)
SwissProt ID

Q9P0K1