AKAP12 Antibody (YA8036)
(Synonyms: AKAP250; SSeCKS)AKAP12 Antibody (YA8036) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to AKAP12.
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Host:
Mouse
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Isotype:
IgG2b
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Application:
IHC-P
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Reactivity :
Human
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|
| Dilution Ratio | 1:500-800 |
Product Details
AKAP12 Antibody (YA8036) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to AKAP12.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Calculated Molecular Weight Predicted band size: 191.3 kDa
Human recombinant protein fragment corresponding to amino acids 266-557 of human AKAP12 produced in E.coli.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG2b
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
AKAP12 is an Anchoring protein that mediates the subcellular compartmentation of protein kinase A (PKA) and protein kinase C (PKC)
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Subcellular Localization
Cytoplasm, cell cortex,Cytoplasm, cytoskeleton,Membrane
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Expression
Tissue_Specificity: Expressed in endothelial cells, cultured fibroblasts and osteosarcoma, but not in platelets, leukocytes, monocytic cell lines or peripherical blood cells
Induction: Activated by lysophosphatidylcholine (lysoPC) -
Isoforms & Post-Translational Modification
Q02952 has three isomers: Q02952-1: 191482 Da (predicted); Q02952-2: 181690 Da (predicted); Q02952-3: 180990 Da (predicted).
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Subunit
Binds to dimeric RII-alpha regulatory subunit of PKC
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SwissProt ID
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Synonyms
AKAP250; SSeCKS
Documentation