alpha 1 Spectrin Antibody (YA1125)
(Synonyms: EL2; Elliptocytosis2; erythrocyte; Erythroid alpha spectrin; HS3; SPH3; SPTA; SPTA1)alpha 1 Spectrin Antibody (YA1125) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to alpha 1 Spectrin.
-
Host:
Rabbit
-
Isotype:
IgG
-
Application:
IHC-P
-
Reactivity :
Human
-
Formulation:
Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.45.
-
Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
|
|---|---|
| Dilution Ratio | 1:100-1:200 |
Product Details
alpha 1 Spectrin Antibody (YA1125) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to alpha 1 Spectrin.
-
Host Rabbit
-
Clonality Recombinant, Monoclonal
-
Species ReactivityHuman
-
Observed Molecular WeightObserved band size: 280 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
-
Calculated Molecular Weight Predicted band size: 280 kDa
A synthesized peptide derived from human alpha 1 Spectrin
Endogenous
Affinity Purified
Non-conjugated
Unmodified
IgG
Product Properties
-
Appearance
Liquid
-
Formulation
Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.45.
-
Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
-
Shipping
Shipping with blue ice.
Background
-
Function
alpha 1 Spectrin is a Spectrin is the major constituent of the cytoskeletal network underlying the erythrocyte plasma membrane. It associates with band 4.1 and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane
-
Subcellular Localization
Cytoplasm, cytoskeleton; Cytoplasm, cell cortex
-
Isoforms & Post-Translational Modification
P02549 has 2 isomers: P02549-1: 280014 Da (predicted); P02549-2: 279674 Da (predicted).
-
Subunit
Composed of non-homologous chains, alpha and beta, which aggregate side-to-side in an antiparallel fashion to form dimers, tetramers, and higher polymers. Interacts with FASLG. Interacts with BCAM (PubMed:15238148)
-
SwissProt ID
-
Synonyms
EL2; Elliptocytosis2; erythrocyte; Erythroid alpha spectrin; HS3; SPH3; SPTA; SPTA1
-
Research Field
Cardiovascular
Documentation
Powered by Bioz
