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  4. Monoclonal Antibodies Recombinant Antibodies
  5. alpha 1 Spectrin Antibody (YA1125)

alpha 1 Spectrin Antibody (YA1125)

Cat. No.: HY-P81380
User Guide for Antibodies Technical Support

alpha 1 Spectrin Antibody (YA1125) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to alpha 1 Spectrin.

For research use only. We do not sell to patients.

Size Price Stock Quantity
20 μL Get quote 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
50 μL Get quote 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
100 μL Get quote 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
250 μL   Get quote  
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Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

  • Product Detail

  • Background

  • Documentation

Description

alpha 1 Spectrin Antibody (YA1125) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to alpha 1 Spectrin.
Host

Rabbit
Clonality

Recombinant, Monoclonal
Molecular Weight
Predicted band size: 280 kDa;
Observed band size: 280 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Species Reactivity
Human
SwissProt ID
Gene ID
Immunogen

A synthesized peptide derived from human alpha 1 Spectrin
Application &
Dilution Ratio
Application Dilution Ratio
IHC-P
IHC-P: Immunohistochemistry-Paraffin
1:100-1:200
Sensitivity Endogenous Purity Affinity Purified
Conjugation Non-conjugated Modification Unmodified
Isotype IgG  
Appearance

Liquid
Formulation

Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.45.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.
Background
Function：Spectrin is the major constituent of the cytoskeletal network underlying the erythrocyte plasma membrane. It associates with band 4.1 and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane
Subcellular Localization：Cytoplasm, cytoskeleton; Cytoplasm, cell cortex
Isoforms & Post-Translational Modification：P02549 has 2 isomers: P02549-1: 280014 Da (predicted); P02549-2: 279674 Da (predicted).
Subunit：Composed of non-homologous chains, alpha and beta, which aggregate side-to-side in an antiparallel fashion to form dimers, tetramers, and higher polymers. Interacts with FASLG. Interacts with BCAM (PubMed:15238148)
Database

Entrez Gene: 6708 Human

SwissProt: P02549 Human

OMIM: 130600 Human

Research Field

Cardiovascular
Synonyms
EL2; Elliptocytosis2; erythrocyte; Erythroid alpha spectrin; HS3; SPH3; SPTA; SPTA1
Documentation
User Guide for Antibodies (1077 KB)

alpha 1 Spectrin Antibody (YA1125) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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alpha 1 Spectrin Antibody (YA1125)
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