AMPK beta 1 Antibody (YA5400)
(Synonyms: 5'-AMP-activated protein kinase subunit beta-1; AMPK subunit beta-1; AMPKb; )AMPK beta 1 Antibody (YA5400) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to AMPK beta 1.
-
Host:
Mouse
-
Application:
IHC-P, WB
-
Reactivity :
Human, Mouse, Rat
-
Formulation:
Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
-
Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC1
|
WB
WB: Western Blot
|
|---|---|---|
| Dilution Ratio | 50-200 | 1:1000-2000 |
Product Details
AMPK beta 1 Antibody (YA5400) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to AMPK beta 1.
-
Host Mouse
-
Clonality Monoclonal
-
Species ReactivityHuman, Mouse, Rat
-
Observed Molecular WeightObserved band size: 38 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Synthesized peptide derived from human AMPKβ1
affinity chromatography.
Non-conjugated
Unmodified
Product Properties
-
Appearance
Liquid
-
Formulation
Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
-
Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
-
Shipping
Shipping with blue ice.
Background
-
Function
AMPK beta 1 is a Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3)
-
Subunit
AMPK is a heterotrimer of an alpha catalytic subunit (PRKAA1 or PRKAA2), a beta (PRKAB1 or PRKAB2) and a gamma non-catalytic subunits (PRKAG1, PRKAG2 or PRKAG3). Interacts with FNIP1 and FNIP2
-
SwissProt ID
-
Synonyms
5'-AMP-activated protein kinase subunit beta-1; AMPK subunit beta-1; AMPKb;
Documentation
Powered by Bioz
