ANGPTL8 Antibody (YA7007)

製品番号: HY-P87324: データシート User Guide for Antibodies
FAQs
Technical Support

ANGPTL8 Antibody (YA7007) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to ANGPTL8.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

容量		在庫状況
50 μL		お問い合わせ
100 μL		お問い合わせ

* アイテムを追加する前、数量をご選択ください

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
説明

製品説明

ANGPTL8 Antibody (YA7007) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to ANGPTL8.

Host

Mouse

Clonality

Monoclonal

分子量

Predicted band size: 22 kDa;

Observed band size: 25 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

Q8R1L8

Immunogen

Recombinant mouse ANGPTL8: 16-198/198

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-2000

Sensitivity	Endogenous	純度	Protein G affinity purified.
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

輸送条件

Shipping with blue ice.

Background

Function：Hormone that acts as a blood lipid regulator by regulating serum triglyceride levels (PubMed:22569073, PubMed:22809513, PubMed:23150577, PubMed:24043787). May be involved in the metabolic transition between fasting and refeeding: required to direct fatty acids to adipose tissue for storage in the fed state (PubMed:24043787). According to a report, may act by promoting ANGPTL3 cleavage (PubMed:23150577). According to another study, not required for cleavage of ANGPTL3 (PubMed:24043787)

Subcellular Localization：Secreted

Expression：
Tissue_Specificity: Expressed in liver and fat. Enriched in white and brown adipose tissues
Induction: Highly up-regulated following high-fat diet treatment. Down-regulated upon fasting. Strongly induced in the cold environment (4 Degrees Celsius for 4 hours)

Subunit：Interacts with ANGPTL3

Database

SwissProt: Q6UXH0 Human

Synonyms

Angiopoietin-like protein 8 antibody; ANGPTL8 antibody; betatrophin antibody; Chromosome 19 open reading frame 80 antibody; hepatocellular carcinoma-associated gene TD26 antibody; Hepatocellular carcinoma-associated protein TD26 antibody; Lipasin antibody; PRO1185 antibody; PVPA599 antibody; RIFL antibody

ドキュメンテーション

User Guide for Antibodies (1077 KB)

ANGPTL8 Antibody (YA7007) 関連分類

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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ANGPTL8 Antibody (YA7007)

Product Detail

Background

説明

ANGPTL8 Antibody (YA7007) 関連分類

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