ANGPTL8 Antibody (YA7007)

Cat. No.: HY-P87324: Data Sheet User Guide for Antibodies
FAQs
Technical Support

ANGPTL8 Antibody (YA7007) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to ANGPTL8.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

* Please select Quantity before adding items.

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

ANGPTL8 Antibody (YA7007) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to ANGPTL8.

Host

Mouse

Clonality

Monoclonal

Molecular Weight

Predicted band size: 22 kDa;

Observed band size: 25 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

Q8R1L8

Immunogen

Recombinant mouse ANGPTL8: 16-198/198

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-2000

Sensitivity	Endogenous	Purity	Protein G affinity purified.
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Hormone that acts as a blood lipid regulator by regulating serum triglyceride levels (PubMed:22569073, PubMed:22809513, PubMed:23150577, PubMed:24043787). May be involved in the metabolic transition between fasting and refeeding: required to direct fatty acids to adipose tissue for storage in the fed state (PubMed:24043787). According to a report, may act by promoting ANGPTL3 cleavage (PubMed:23150577). According to another study, not required for cleavage of ANGPTL3 (PubMed:24043787)

Subcellular Localization：Secreted

Expression：
Tissue_Specificity: Expressed in liver and fat. Enriched in white and brown adipose tissues
Induction: Highly up-regulated following high-fat diet treatment. Down-regulated upon fasting. Strongly induced in the cold environment (4 Degrees Celsius for 4 hours)

Subunit：Interacts with ANGPTL3

Database

SwissProt: Q6UXH0 Human

Synonyms

Angiopoietin-like protein 8 antibody; ANGPTL8 antibody; betatrophin antibody; Chromosome 19 open reading frame 80 antibody; hepatocellular carcinoma-associated gene TD26 antibody; Hepatocellular carcinoma-associated protein TD26 antibody; Lipasin antibody; PRO1185 antibody; PVPA599 antibody; RIFL antibody

Documentation

User Guide for Antibodies (1077 KB)