APC-conjugated CD42a Antibody (GR-P)
(Synonyms: CD42a,CD42a-APC,GR-P)APC-conjugated CD42a Antibody (GR-P) is a Mouse-derived and APC conjugated monoclonal antibody, targeting to CD42a.
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Host:
Mouse
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Isotype:
Mouse IgG1,κ
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Application:
FC
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Reactivity :
Human
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Formulation:
Supplied in PBS (pH 7.2) containing 0.1% Proclin300 and protein stabilizer.
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Conjugation:
APC
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
FC
FC: Flow Cytometry
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|---|---|
| Dilution Ratio | 5 ul per 106 cells in a 100 µl suspension |
Product Details
APC-conjugated CD42a Antibody (GR-P) is a Mouse-derived and APC conjugated monoclonal antibody, targeting to CD42a.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
APC
Unmodified
Mouse IgG1,κ
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH 7.2) containing 0.1% Proclin300 and protein stabilizer.
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Storage & Stability
Stored at 2-8°C for 1 year, protect from light, do not freeze.
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Shipping
Shipping with blue ice.
Background
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Function
CD42a is a platelet membrane glycoprotein encoded by the GP9 gene and is an important component of the GPIb-IX-V complex. CD42a is mainly expressed in platelets and megakaryocytes. Although it does not directly bind to vWF, it is crucial for the stable expression and normal function of the complex. CD42a participates in the initial adhesion of platelets to damaged blood vessel walls and is a key early molecule in the hemostatic response. CD42a is an important pathogenic protein associated with Bernard-Soulier syndrome and is also a commonly used biomarker in megakaryocyte differentiation, AML-M7 immunophenotyping, and platelet function testing.
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Isoforms & Post-Translational Modification
CD42a: 177 amino acids, molecular weight 19046 Da.
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Subunit
Two GP-Ib beta are disulfide-linked to one GP-Ib alpha
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Synonyms
CD42a,CD42a-APC,GR-P
Documentation
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