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ASL Antibody (YA7790)(PBS only)

(Synonyms: ASAL)

ASL Antibody (YA7790) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to ASL.

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG2a

  • Application:

    IHC-P

  • Reactivity :

    Human, Mouse, Rat

  • Formulation:

    Supplied in PBS, pH 7.4.

  • Conjugation:
    Non-conjugated
  • ASL Antibody (YA7790)(PBS only) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
Dilution Ratio 1:100-500

Product Details

Description

ASL Antibody (YA7790) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to ASL.

  • Host Mouse
  • Species Reactivity
    Human, Mouse, Rat
  • Calculated Molecular Weight Predicted band size: 51.5 kDa
Immunogen

Full length human recombinant protein of human ASL produced in HEK293T cell.

Purification

Affinity purified

Conjugation

Non-conjugated

Isotype

IgG2a

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS, pH 7.4.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    ASL catalyzes the reversible cleavage of L-argininosuccinate to fumarate and L-arginine, an intermediate step reaction in the urea cycle mostly providing for hepatic nitrogen detoxification into excretable urea as well as de novo L-arginine synthesis in nonhepatic tissues. Essential regulator of intracellular and extracellular L-arginine pools. As part of citrulline-nitric oxide cycle, forms tissue-specific multiprotein complexes with argininosuccinate synthase ASS1, transport protein SLC7A1 and nitric oxide synthase NOS1, NOS2 or NOS3, allowing for cell-autonomous L-arginine synthesis while channeling extracellular L-arginine to nitric oxide synthesis pathway[1][2][3][4][5].

  • Isoforms & Post-Translational Modification

    P04424 has three isomers: P04424-1: 51658 Da (predicted); P04424-2: 49509 Da (predicted); P04424-3: 48733 Da (predicted).
    Acetylation modifies enzyme activity in response to alterations of extracellular nutrient availability

  • Subunit

    Homotetramer (PubMed:11747433)

  • SwissProt ID

    P04424

  • Synonyms

    ASAL

ASL Antibody (YA7790)(PBS only) Related Classifications

MOQ
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100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
  • ASL Antibody (YA7790)(PBS only) Product Image
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  • ASL Antibody (YA7790)(PBS only) Product Image